TY - JOUR ID - 10821 TI - Coronary Artery Bypass Graft in Six Members of a Family: A Case Series JO - Journal of Cardio-Thoracic Medicine JA - JCTM LA - en SN - 2345-2447 AU - Alizadeh, Kambiz AU - Ghodsi, Majid AU - Mahdavi, Maryam AU - Zargaran, Bita AU - Alavinejad, Roghaye AU - Tabari, Masoomeh AD - Cardio Surgeon, Department of Cardiovascular Surgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran AD - Cardio Surgeon, Department of Cardiovascular Surgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. AD - Dermatologist, Department of Dermatology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran AD - Student Research Committee, Faculty of Medicine, Islamic Azad University, Mashhad Branch, Mashhad, Iran. AD - Msc in Medical Surgical Nursing Education, Research Assistant of Department Of Cardiovascular Surgery, Faculty Of Medicine, Mashhad University Of Medical Sciences. AD - Anaesthesiologist, Department of Anaesthesiology, Faculty Of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Y1 - 2018 PY - 2018 VL - 6 IS - 2 SP - 291 EP - 294 KW - Genetics KW - Coronary Artery Disease KW - Coronary artery bypass grafting DO - 10.22038/jctm.2018.30629.1157 N2 - Abstract: Coronary artery disease (CAD) is a multifactorial problem. Although hyperlipidemia (HLP), diabetes (DM), and hypertension (HTN) are known as the familial and cardiac risk factors, CABG is rare in the several members of a family. We reported the six members of a family who presented with MI and/or advanced angina pectoris during the 6 years. CABG(Coronary artery bypass graft) considered for all patients due to involvement in main coronary arteries and clinical presentation. The ejection fraction (EF) was varied between 25% to 70%. Beating heart cardiopulmonary bypass (beating heart CPB) and off-pump were chosen as surgical method. The mean duration of surgery was about 4 hours. The only post-operative complication was deep wound infected in a young man who was smoker and drug abuser. According to family relationship of patients and the high effect of genetic penetration, we presume the gene influence to incidence CAD and potential to undergoing CABG, in members of a special family. UR - https://jctm.mums.ac.ir/article_10821.html L1 - https://jctm.mums.ac.ir/article_10821_c48544a5c621596b66c523ad87460097.pdf ER -