TY - JOUR ID - 9236 TI - An Unusual Presentation of Granulomatosis with Polyangiitis JO - Journal of Cardio-Thoracic Medicine JA - JCTM LA - en SN - 2345-2447 AU - Sodhi, Rakhee AU - Khanduri, Sushant AU - Jethani, Varuna AU - Nadia, Shirazi AU - Kumar, Manoj AD - Internal Medicine, Pulmonologist, Department of Pulmonary Medicine, Himalayan Institute of Medical Sciences, Dehradun,Indian AD - Critical Care Medicine, Department of Critical Care Medicine, Himalayan Insitute of Medical Sciences, Dehradu, Indian AD - Senior Resident, Department of Pulmonary Medicine, Himalayan Institute of Medical Sciences, Dehradun, Indian AD - Pathologist, Department of Pathology, Himalayan Institute of Medical Sciences, Dehradun, Indian AD - Resident, Department of Pulmonary Medicine, Himalayan Institute of Medical Sciences, Dehradun, Indian Y1 - 2017 PY - 2017 VL - 5 IS - 3 SP - 204 EP - 207 KW - Antinuclear antibody KW - Anti-neutrophil cytoplasmic antibody KW - Granulomatosis With Polyangiitis KW - Sepsis DO - 10.22038/jctm.2017.24298.1135 N2 - The granulomatosis with polyangiitis (GPA), formerly known as Wegener’s granulomatosis, is a pauci-immune vasculitis involving small- and medium-sized blood vessels. Classically, the patients inflicted with this disease present with a triad of necrotizing granulomatous inflammation of the respiratory tract, cutaneous necrotizing vasculitis, and glomerulonephritis (GN). The antinuclear (ANA) and anti-neutrophil cytoplasmic antibodies (ANCA) are considered as relatively specific markers of the disease. Herein, we presented the case of a patient who initially presented with sepsis but did not respond to the conventional antibiotics and later diagnosed with GPA.The granulomatosis with polyangiitis (GPA), formerly known as Wegener’s granulomatosis, is a pauci-immune vasculitis involving small- and medium-sized blood vessels. Classically, the patients inflicted with this disease present with a triad of necrotizing granulomatous inflammation of the respiratory tract, cutaneous necrotizing vasculitis, and glomerulonephritis (GN).The antinuclear (ANA) and anti-neutrophil cytoplasmic antibodies (ANCA) are considered as relatively specific markers of the disease. Herein, we presented the case of a patient who initially presented with sepsis but did not respond to the conventional antibiotics and later diagnosed with GPA. UR - https://jctm.mums.ac.ir/article_9236.html L1 - https://jctm.mums.ac.ir/article_9236_b5d86aad598b97d478f58cad806e8335.pdf ER -