Serum vitamin D level and hypertensive crises

Document Type: Original Article


1 Cardiologist, Cardiovascular Research Center, Institute of Basic and Clinical Physiology Sciences, School of Health, Kerman University of Medical Sciences, Kerman, Iran

2 Resident of cardiology, Clinical Research Unit, Shafa Hospital, Kerman University of Medical Sciences, Kerman, Iran

3 Community medicine, Social Determinants of Health Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran


Introduction :Vitamin D deficiency is associated with hypertension; however, there is no study on the relationship between vitamin D deficiency and hypertensive crises. This study aimed to determine the relationship between serum vitamin D levels and hypertensive crises.
Materials and Methods: This descriptive-analytical, cross-sectional study was conducted on 120 individuals in Shafa Hospital in 2016 within the age range of 40-80 years, selected through simple random sampling technique. The research population was divided into two groups of hypertensive crises (n=60) with blood pressure over 180/120 mm/Hg and hypertensive patients without history of hypertension crises (n=60). For the purpose of the study, 5 ml peripheral venous blood samples were collected. The blood serum was isolated by a centrifugal device, and the serum vitamin D levels were analyzed by radioimmunoassay.
Results: The meanlevels ofvitamin D in hypertensive and non- hypertensive crises groups were 29.73 and 30.23 ng/ml, respectively. There was no significant difference between the two groups in terms of vitamin D levels (P>0.05). However, no statistically significant difference was observed between the two groups considering gender (P>0.05). Serum vitamin D levels showed a direct correlationwith theduration of hypertension and age (P Conclusion:There is evidence on the relationship between serum vitamin D levels and cardiovascular diseases, including hypertension. Nonetheless, in the present study, no significant relationship was observed between serum vitamin D level and hypertensive crises.


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