Spirometric Parameters: Hemodialysis Compared to Peritoneal Dialysis

Document Type: Original Article

Authors

1 Pulmonologist, Lung Disease Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Ir

2 Nephrologist, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

3 Fellowship of Cardiology, Faculty of Medicine, Mashhad University of Medical Sciences, Iran

4 Resident of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

5 Pulmonologist, Cardio-Thoracic Surgery & Transplant Research Center, Emam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

6 Pulmonologist, Lung Disease Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract

Introduction: Renal failure affects the mechanical and the ventilatory function of the lungs. A few studies have evaluated the ventilatory and pulmonary function in dialysis patients. The present study aimed to compare Pulmonary Function Test (PFT) results in patients undergoing Hemodialysis (HD) and Peritoneal Dialysis (PD).
Materials and Methods: We conducted a cross-sectional study on 50  patients with hemodialysis (HD) and 50 cases with PD who  underwent PFT in Ghaem and Imam Reza hospitals Mashhad, Iran from November 2010 to July 2012. Spirometric parameters including forced expiratory volume in 1s (FEV1), FEV1/forced vital capacity (FVC), forced expiratory flow 25-75% (FEF) and peak expiratory flow (PEF) were compared between the two groups of patients.
Results: Approximately 68% of the HD patients, 66% of the PD patients, and 67% of all the studied cases showed a normal spirometric pattern. Moreover, there were no significant differences between the two groups considering the mean of the aforementioned spirometric parameters(restrictive ,obstructive pattern) (P=0.969). However, an insignificant inverse correlation was observed between the duration of dialysis with FEV1 (r=0.381, P=0.008), FVC (r=-0.298, P=0.04), FEF 25-75% (r=0.43, P=0.003), PEF (r= 0.349, P=0.02) and FEV1/FVC (r=-0.363, P=0.01,) in the HD patients and between the patients’ age with FEV1/FVC (r=0.03, P=0.02) in the PD patients.
Conclusion: This study showed no significant difference in pulmonary function in hemo and peritoneal dialysis,so according this result ,both of the dialysis had the same affect on the lung function.

Keywords


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