A Game Changer for Low and Middle Income Countries: Del Nido Cardioplegia for Adult Cardiac Surgery – A Tertiary Care Experience

Articles in Press

Document Type : Original Article

Authors

1 Gujarat cancer society Medical college

2 GUJARAT CANCER SOCIETY MEDICAL COOLEGE , HOSPITAL AND RESEARCH CENTER

3 COLLEGE OF DENTAL SCIENCES AND HOSPITAL

10.22038/jctm.2026.91104.1508

Abstract

Objectives

Del Nido Cardioplegia (DNC) provides prolonged myocardial protection with a single-dose strategy.



Methods

This retrospective study included 175 adult patients across five surgical groups (DVR, MIS‑MVR, MVR via sternotomy, AVR, congenital repairs). Statistical analysis was performed using SPSS v25. Quantitative variables were analyzed using t‑test/Mann–Whitney U; categorical variables using chi‑square/Fisher’s exact. Comparisons across groups yielded statistically significant differences (p<0.05) for ACC and CPB durations.



Results

Spontaneous sinus rhythm return ranged from 90–100% across groups. ACC and CPB times varied significantly (p<0.05). Single‑dose DNC was adequate in all cases.



Conclusion

DNC is safe and resource‑efficient in LMIC settings.

Keywords

Journal of Cardio-Thoracic Medicine

Articles in Press, Accepted Manuscript
Available Online from 27 January 2026

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