PERIOPERATIVE PREDICTORS OF ACUTE KIDNEY INJURY IN OFFPUMP CORONARY ARTERY BYPASS GRAFTING SURGERY

Articles in Press

Document Type : Original Article

Authors

U.N.Mehta Institute of Cardiology and Research Center Ahmadabad, Gujarat

10.22038/jctm.2026.93926.1524

Abstract

Introduction

Acute kidney injury (AKI) after cardiac surgery is associated with increased morbidity and mortality. Risk factors for AKI during off-pump coronary artery bypass grafting (OPCAB) are poorly understood our aim of this study is to identify the relationship between perioperative parameters and AKI following OPCAB.

Method

This prospective observational study conducted in a single tertiary cardiac centre. A total of 175 patients undergoing elective isolated CABG were included in this study over a period of 2 years (March 2021 – February 2023). Out of 175 patients; 34 patients developed acute kidney injury after off pump coronary artery bypass grafting surgery. Their preoperative, intraoperative and postoperative findings were compared to find out the Independent risk factors for developing postoperative acute kidney injury.

Result

The study conducted on 175 patients: 113 males (64.5%) and 62 females (35.5%). Their age ranged from 61.81±8.30 years. In AKI group patients Independent risk factors for developing postoperative AKI consist of Age>70 years (P<0.0001), BMI>30kg/m2 (P=0.015), Diabetes, High HbA1c level (>6.5%) (P=<0.001), Hypertension (P<0.001), no intake of calcium channel blocker for hypertension (P=<0.001), EF<30% and Timing of angiography before surgery (<14days) (P=0.005).





Conclusion

Independent risk factors for developing postoperative AKI consist of Age>70 years, BMI>30kg/m2, Diabetes, High HbA1c level (>6.5%), Hypertension, no intake of calcium channel blocker for hypertension, EF<30%, Timing of angiography before surgery (<14days), Acute MI (<30 days), High serum lactate level at 12 hours post ICU admission, High vasoactive inotropic score, Requirement of blood transfusion due to various reason. Among all these variables mortality found as strong predictor in AKI group patients (p=0.016, or=14.95, 95%CI 1.64-136.08).

Keywords

Journal of Cardio-Thoracic Medicine

Articles in Press, Accepted Manuscript
Available Online from 09 February 2026

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