Cardiac Complication Following Subarachnoid Hemorrhage
Mahmoud
Shabestari
Cardiologist,Cardiac Department, Mashhad University of Medical Sciences, Mashhad, Iran
author
Raphael
Blanc
Neuroradiologist, Interventional Neuroradiology Department, Hospital of Rothschild Roundation, Paris 75019, France
author
Humain
Baharvahdat
Endovascular Neurosurgeon, Department of Neurosurgery, Ghaem Hospital, Mashhad University of Medical Sciences,Mashhad,Iran
author
Hamzeh
Dehganizadeh
Neurosurgeon, Department of Neurosurgery, Ghaem Hospital, Mashhad University of Medical Sciences,Mashhad
author
Michel
Piotin
Neuroradiologist, Interventional Neuroradiology Department, Hospital of Rothschild Roundation, Paris 75019, France
author
text
article
2018
eng
Besides its severe neurological injuries, spontaneous subarachnoid hemorrhage (SAH) commonly causes cardiac complications. These complications could include three different aspects of cardiac diseases, that is, electrocardiographic abnormalities, myocardial injuries, and left ventricular dysfunction. These complications not only may lead to misdiagnosis of SAH as myocardial infarction, but also it may complicate the management of SAH. In this review, we described all cardiac complications during SAH and explained the appropriate monitoring and management of these problems
Journal of Cardio-Thoracic Medicine
Mashhad University of Medical Sciences
2345-2447
6
v.
3
no.
2018
313
318
https://jctm.mums.ac.ir/article_11375_ed204b9c26b6eb74f9c304a8c3822635.pdf
dx.doi.org/10.22038/jctm.2018.32692.1170
Responses of Muscle Mitochondrial Function to Physical Activity: A Literature Review
keyvan
Hejazi
Physiologist, Department of Exercise and Sport Physiology, Faculty of Sport Sciences, Toos Institute of Higher Education, Mashhad, Iran
author
text
article
2018
eng
Skeletal muscles play an active role in regulating the metabolic homeostasis through their ability for relating to adipose tissue and endocrine hormones. Contraction of the skeletal muscle leads to increased release of several myokines, such as irisin, which is able to interact with the adipose tissue. Physical activity promotes the irisin mechanism by augmenting the peroxisomes (PGC1-α) in the skeletal muscle. Afterwards, an elevation occurs in the membrane protein of fibronectin type III domain-containing protein 5 (FNDC5) in muscle, ultimately resulting in production of irisin. The expression of irisin and FNDC5 converts white adipose into the brown type and increases energy consumption by the whole body hindering obesity and diabetes. The effects of regular exercise training on preventing obesity, diabetes, and the related complications, as well as improving health have already been proven. However, the point is that these beneficial effects are due to the cellular-molecular mechanisms, which are still under discussion. In this review, we searched the online databases, including scientific information database (SID), Google Scholar, PubMed, Science Direct, and Scopus. The following keywords were used: training, physical activity, myokine, adipose tissue, PRDM16, PGC-1α, PPARγ, SIRT1, FGF21, bone morphogenetic protein, neurugolin, VEGF, and IL-15. All the articles, including research studies, review articles, descriptive and analytical studies, in addition to cross-sectional researches published during 1998-2017 were reviewed. According to the obtained results, it seems that expression of irisin and FNDC5 converts the white adipose into brown adipose resulting in increased energy consumption. It has been proven in the literature that regular exercise training prevents obesity, diabetes, and the related complications, as well as improving health.
Journal of Cardio-Thoracic Medicine
Mashhad University of Medical Sciences
2345-2447
6
v.
3
no.
2018
319
328
https://jctm.mums.ac.ir/article_11376_5ca1e99e23d650136ea2299f6640d717.pdf
dx.doi.org/10.22038/jctm.2018.32946.1171
The Critical-Care Pain Observation Tool: A useful tool for pain assessment in intensive care units
Reza
Basiri
Pulmonologist, Lung Disease Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
author
Mohaddeseh
Ghelichli
Resident of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Shahrzad
M Lari
Pulmonologist, Lung Diseases Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
sepide
hejazi
Pulmonologist, Lung Diseases Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Ali
Vahidi Rad
Resident of Surgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
text
article
2018
eng
Pain is a major concern in all intensive care units (ICUs). The proper assessment and management of pain is one of the main goals of patient care in ICUs. Improper evaluation of pain and its over or under treatment can cause significant problems in the process of patient management in ICU. Since most ICU patients are unable to communicate correctly with the ICU team and explain their level of pain, pain assessment can be challenging. Thus, several assessment tools for the evaluation of pain were developed, few of which were validated. Critical Care Pain Observation Tool is a valid and reliable instrument for pain assessment in different ICUs.
Journal of Cardio-Thoracic Medicine
Mashhad University of Medical Sciences
2345-2447
6
v.
3
no.
2018
329
331
https://jctm.mums.ac.ir/article_11374_fbc43db5e568e031ac95a3788e13d15f.pdf
dx.doi.org/10.22038/jctm.2018.32648.1169
Consequences of coronary artery bypass grafting in smokers and addicts
Behrouz
Mottahedi
Cardiovascular Surgeon, Faculty of Medicine, Mashhad University Of Medical Sciences, Mashhad, Iran.
author
Majid
Ghodsi
Cardiovascular Surgeon, Faculty of Medicine ,Department Of Cardiovascular Surgery, Faculty Of Medicine, Mashhad University Of Medical Sciences, Mashhad, Iran
author
Bita
Zargaran
Student Research Committee, Faculty of Medicine, Islamic Azad University, Mashhad Branch, Mashhad, Iran.
author
Saeedeh
Hajebi Khaniki
Msc Student Of Biostatistics, Social Determinants Of Health Research Center, Mashhad University Of Medical Sciences, Mashhad, Iran.
author
Mahnaz
Komeilipour
Student Research Committee, Faculty of Medicine, Islamic Azad University, Mashhad Branch, Mashhad, Iran.
author
Mahdi
Kahrom
Cardio Surgeon, Department of Cardiovascular Surgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
author
text
article
2018
eng
Introduction: The most common cardiac disease is coronary artery disease (CAD) in the world. Coronary artery bypass grafting (CABG) is implemented through two standard surgical techniques, namely off-pump beating-heart CABG (OPCABG) and on-pump CABG (ONCABG). The CABG results in various levels of morbidity, especially in smokers and addicts, who have a lower pain threshold. Regarding this, the aim of this study was to clarify several aspects of the consequences of CABG, especially in smokers and addicts. Materials and Methods: This cross-sectional study was conducted on 125 CABG candidates referring to the Cardiac Department of Ghaem Hospital in Mashhad, Iran, within 2014-2015. The patients underwent either OPCAB or ONCABG. The recorded data included the type and dosage of intra- and post-operative opioids used for the induction and maintenance of anaesthesia, as well as the volume of packed red blood cells, fresh frozen plasma, and platelet. Data analysed using IBM SPSS 19.0 and p-value less than 0.05 considered statistically significant. Result: According to the results, the mean age of the patients were 59.4±9.8 years. Out of the 125 participants, 89 and 36 patients underwent ONCABG and OPCABG, 71.9% and 58.3% of whom were male, respectively. The sufentanil dose administered for the induction of anaesthesia was 9.9±2.7 cc in the smokers, which was significantly higher in comparison to the dose (7.3±2.1 cc) used for the non-smokers (P=0.015). Furthermore, the mean doses of dobutamine used for the addicted and non-addiced patients were 4.4±1.8 and 5.5±2.2 cc, respectively, which was significantly different between the two groups (P=0.037). Conclusion: The ONCABG is a common surgical technique, which is used in patients with a more coronary vessel involvement. This study has demonstrated that although the same opioid anaesthetic drugs were used for the smokers and addicted patient, the dose of administered sufentanil was significant different between smokers and non-smokers.
Journal of Cardio-Thoracic Medicine
Mashhad University of Medical Sciences
2345-2447
6
v.
3
no.
2018
332
337
https://jctm.mums.ac.ir/article_11372_1b1f436076152385f867602006f56ebb.pdf
dx.doi.org/10.22038/jctm.2018.32590.1168
Is Subclinical Thyroid Dysfunction Associated With with Coronary Heart Disease?
Elaheh
Barghchi
Internal Medicine, Department of Endocrinology, University of Medical Sciences, Mashhad, Iran.
author
Fereidoun
Azizi
Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
author
text
article
2018
eng
Introduction: Previous cohort studies reported contradictory data on the association between subclinical thyroid dysfunction and coronary heart disease (CHD). Regarding this, the present study was conducted to illuminate this relationship. Materials and Methods: For the purpose of the study, 3,066 participants employed in a study conducted by Azizi et al. aged ≥ 20 years were subjected to thyroid function tests every 3 years over a mean follow-up of 10 years. After the exclusion of the subjects with CHD and those consumed thyroid, anti-thyroid, or corticosteroid preparations, 2,144 subjects remained for analysis and followed up for CHD events in the next 10 years. Results: At the baseline, 1929, 139, and 76 subjects had euthyroid, subclinical hyperthyroid, and subclinical hypothyroid, respectively. No CHD event occurred in the subclinical hypothyroid group. After the adjustment of all confounders, the subclinical hyperthyroid group had the hazard ratio of 1.01 for CHD with a 95% confidence interval of 0.36-2.85. Conclusions: The 10 year follow-up of subjects with subclinical thyroid disease revealed no relationship between CHD and subclinical thyroid disorders.
Journal of Cardio-Thoracic Medicine
Mashhad University of Medical Sciences
2345-2447
6
v.
3
no.
2018
338
343
https://jctm.mums.ac.ir/article_11377_60cdac69b591a43b32d8ef43ad2def43.pdf
dx.doi.org/10.22038/jctm.2018.33242.1172
Cardiac Myxoma, a Rare But Most Common Encountered Cardiac Tumor: A Single Center Experience
Satish
Das
Cardiovascular and Thoracic Surgeon, Department of Cardiovascular & Thoracic Surgery, Government medical college & Super speciality Hospital, Nagpur 440009 , Maharashtra, India.
author
Chandan
Ray Mohapatra
Cardiovascular and Thoracic Surgeon, Department of Cardiovascular & Thoracic Surgery, Government medical college & Super speciality Hospital, Nagpur 440009 , Maharashtra, India.
author
Ashish
Badkhal
Cardiovascular and Thoracic Surgeon, Department of Cardiovascular & Thoracic Surgery, Government medical college & Super speciality Hospital, Nagpur 440009 , Maharashtra, India.
author
Sudhir
Dhande
Cardiovascular and Thoracic Surgeon, Department of Cardiovascular & Thoracic Surgery, Government medical college & Super speciality Hospital, Nagpur 440009 , Maharashtra, India.
author
Pankaj
Pohekar
Cardiovascular and Thoracic Surgeon, Department of Cardiovascular & Thoracic Surgery, Government medical college & Super speciality Hospital, Nagpur 440009 , Maharashtra, India.
author
Ambrish
Khatod
Cardiovascular and Thoracic Surgeon, Department of Cardiovascular & Thoracic Surgery, Government medical college & Super speciality Hospital, Nagpur 440009 , Maharashtra, India.
author
text
article
2018
eng
Introduction: Cardiac myxoma is a benign and rare tumor, which can present with a grim phenomenon if the presentation is late or the diagnosis and surgery are delayed. The purpose of this study was to share our institutional experience of cardiac myxoma. Material and Methods: This retrospective study was conducted to evaluate patients undergoing procedures at a single tertiary care centre for the treatment of cardiac myxoma during January, 2007 to December, 2017. Preoperative diagnosis was made by assessing clinical presentation and doing echocardiography. Complete tumor excision was performed, and all the patients were followed up for recurrence and complications. Results: A total of 45 cases of cardiac myxoma (13 males and 32 females) with the mean age of 37.5 years old (ranged between 16 and 60 years old) were operated over the period of 10 years. Cardiac myxoma constituted about 0.69% of all cardiac cases operated at our institute. Out of all the subjects, 41, 3, and 1 cases had left atrial, right atrial, and right ventricular involvements, respectively. Additionally, 43 patients (95%) survived the surgery, one recurrence was observed during the follow-up period. Conclusion: Cardiac myxoma is the most common cardiac tumor account for very small percentage of patients with heart disease. Early clinical suspicion and the use of imaging modalities are key to early diagnosis of this condition. Although these tumors have a risk for severe cardiac and systemic symptoms, referral to experienced centers for prompt surgical resection under cardiopulmonary bypass provides excellent early and long-term results.
Journal of Cardio-Thoracic Medicine
Mashhad University of Medical Sciences
2345-2447
6
v.
3
no.
2018
344
349
https://jctm.mums.ac.ir/article_11371_2a182971d33a1e9b281599ccad7afd03.pdf
dx.doi.org/10.22038/jctm.2018.32303.1166
A very rare case of metachronous multicentric giant cell tumor of bone with benign lung metastasis in form of a very large mass lesion
Shekhar
Gangadhar Kadam
Respiratory Medicine, Department Of Respiratory Medicine, Jaslok Hospital And Research Center, Edarm (Ers),Idccm, Fnab, Edic, Fccp
author
Susheel
Bindroo
Respiratory Medicine, Department Of Respiratory Medicine, Jaslok Hospital And Research Center, India
author
Jithin
Krishnan
Respiratory Medicine, Department Of Respiratory Medicine, Jaslok Hospital And Research Center, India
author
Hina
Jayantilal Shah
Nuclear Medicine, Department Of Nuclear Medicine, Jaslok Hospital And Research Centre, India
author
Vikram
Ramchandra Lele
Nuclear Medicine, Department Of Nuclear Medicine, Jaslok Hospital And Research Center, India
author
Ganapathi
Bhat
Oncologist, Department of Medical Oncology,Jaslok Hospital And Research Center, India
author
text
article
2018
eng
Giant cell tumour (GCT) is a benign, locally aggressive tumour of the bone that accounts for 5% of primary bone tumours and 21% of benign bone tumours. This tumour more commonly presents as a single (solitary) lesion; however, it may appear with multiple (multicentric) lesions in less than 1% of the cases. According to the literature, 1-9% of solitary GCTs metastasizes to the lung, more commonly in cases with local recurrence. There are limited case reports on multicentric GCT (MCGCT) in the literature. The MCGCT can be synchronous or metachronous depending upon the time interval between the two lesions. Herein, we presented a very rare case of metachronous MCGCT with benign lung metastasis in form of a huge lung mass.
Journal of Cardio-Thoracic Medicine
Mashhad University of Medical Sciences
2345-2447
6
v.
3
no.
2018
350
354
https://jctm.mums.ac.ir/article_11373_87830593a3da274dd26fc94c23c6323f.pdf
dx.doi.org/10.22038/jctm.2018.32639.1167
Late lumen loss in thoracic aortic end graft after endovascular procedure of a traumatic pseudoaneurysm
Asal
Yadollahi
Cardivascolar Department, Ghaem Hospital, Mashhad university of medical science, Mashhad, Iran
author
Aliasghar
Moeinipour
Cardiac Surgeon, Department of Cardiac Surgery, Mashhad University of Medical Sciences, Mashhad, Iran
author
Hamid
Hoseinikhah
Cardiac Surgeon, Department of Cardiac Surgery, Mashhad University of Medical Sciences, Mashhad, Iran
author
Javad
Ramezani
Cardiologist, Atherosclerosis Prevention Research Center and Department of Cardiovascular, Mashhad University of Medical Sciences, Mashhad, Iran
author
text
article
2018
eng
We report the case of a 23-year-old woman who died due to endograft stenosis 20 months after thoracic endovascular aortic repair. The patient presented with the pseudocoarctation syndrome. Although angioplasty of stenosis endograft was successfully performed, severe metabolic complications were lethal.
Journal of Cardio-Thoracic Medicine
Mashhad University of Medical Sciences
2345-2447
6
v.
3
no.
2018
355
359
https://jctm.mums.ac.ir/article_11370_e991bcbd368b9322eb54ef1fa7f52a6e.pdf
dx.doi.org/10.22038/jctm.2018.31635.1162