ORIGINAL_ARTICLE
Comparative Study on the Effect of Prime Solution Included Dexamethasone Vs. Methyl Prednisone on Incidence of Postoperative Delirium in Patients with Open Heart Surgery by Cardio Pulmonary Bypass Circuit
Introduction: Delirium is a fluctuating type of cognitive impairment and is common in hospitalized patients and after open heart surgery has been reported up to 90%, which leads to increased risk of dementia and hospitalization costs, reduced quality of life, risk of falls. Needs long-term care and etc. Activation of the deep inflammatory response dependent on the blood response and the cardiopulmonary pump circuit is one possible reason for this. Therefore, in this study, two anti-inflammatory drugs, dexamethasone and methylprednisolone, were used in Prime solution in cardiac surgery patients and then the occurrence of delirium was evaluated Methods and Materials: In this clinical trial study with a sample volume size 43 patients in open-heart surgery by on-pump method, after random assignment to two groups including dexamethasone and methylprednisolone that were added to prime solution. Inclusion criteria were EF more than 30%, candidate for mitral valve surgery, absence of cognitive impairment and preoperative delirium and age range 30-65 years. In the first group with 21 patients received dexamethasone at a dose of 0.1 mg/ kg and in the second group with 22 patients at a dose of 0.4 mg/Kg in prime solution. Then delirium examined with standard CAM-ICU instruments after extubation and then the results were analyzed with SPSS 21 version. Results: The results showed that only 18% of patients who received methylprednisolone primer solution and 28% of patients who received dexamethasone primer solution had delirium, and this difference was non-significant (P. value: 0.448). Conclusion: In this study, the anti-inflammatory drug methylprednisolone were not superior to each other and had a similar effect on delirium
https://jctm.mums.ac.ir/article_17639_d4dda36f44804295df71ec5a8b318e25.pdf
2021-03-01
734
738
10.22038/jctm.2021.55572.1314
Delirium
open-heart surgery
Dexamethasone
Methylprednisolone
Mahdi
Fathi
fathim@mums.ac.ir
1
Anesthesiologist, Department of Anesthesiology, Mashhad University of Medical Sciences, Mashhad, Iran
AUTHOR
Majid
Alizadeh
majid.alizadeh.nurs91@gmail.com
2
Department of Extra-Corporeal Circulation (ECC),Imam Reza hospital, Mashhad University of Medical Sciences, Mashhad, Iran,
LEAD_AUTHOR
Lida
Jarahi
jarahil@mums.ac.ir
3
Community Medicine, Department of Community Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
AUTHOR
Ali Asghar
Moeinipoor
moeinipoora1@mums.ac.ir
4
Cardiac Surgeon, Department of Cardiac Surgery, Mashhad University of Medical Sciences, Mashhad, Ira
AUTHOR
Nahid
Zirak
zirakn@mums.ac.ir
5
Anesthesiologist, Department of Anesthesiology, Mashhad University of Medical Sciences, Mashhad, Iran
AUTHOR
Akram
Hoseini
akram.hoseini.nurs91@gmail.com
6
M.Sc Nursing, 17 Shahrivar Hospital, Mashhad, Iran.
AUTHOR
1. Joudi M, Fathi M, Harati H, Joudi M, Izanloo A, Rahdari A, et al. Evaluating the incidence of cognitive disorder following off-pump coronary artery bypasses surgery and its predisposing factors. Anesthesiol Pain Med. 2014 Oct 1;4(4):1–4.
1
2. Jones D, Matalanis G, Mårtensson J, Robbins R, Shaw M, Seevanayagam S, et al. Predictors and Outcomes of Cardiac Surgery-Associated Delirium. A Single Centre Retrospective Cohort Study. Hear Lung Circ. 2019 Mar 1;28(3):455–63.
2
3. Royse CF, Saager L, Whitlock R, Ou-Young J, Royse A, Vincent J, et al. Impact of Methylprednisolone on Postoperative Quality of Recovery and Delirium in the Steroids in Cardiac Surgery Trial: A Randomized, Double-blind, Placebo-controlled Substudy. Anesthesiology. 2017 Feb 1;126(2):223–33.
3
4. Rezaee F. Translation of Kaplan and Sudock Synopsis of Psyhiatry Behavioral Science. 11th ed. Tehran: Arjmand Publications; 2018. 108 p.
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5. Bruggemans EF. Cognitive dysfunction after cardiac surgery: Pathophysiological mechanisms and preventive strategies. Netherlands Hear J. 2013;21(2):70–3.
5
6. Glumac S, Kardum G, Sodic L, Supe-Domic D, Karanovic N. Effects of dexamethasone on early cognitive decline after cardiac surgery; A randomised controlled trial. Eur J Anaesthesiol. 2017;34(11):776–84.
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7. Hosseini F, Shajari A, Hosseini B sadat. Investigation of The Frequency of Delirium in Different Departments in the Yazd Shohadaye Kargar Hospital. J Shahid Sadoughi Univ Med Sci. 2016;48(8):640–8.
7
8. Chamani J. Energetic domains analysis of bovine α-lactalbumin upon interaction with copper and dodecyl trimethylammonium bromide. Journal of Molecular Structure. 2010; 979(1-3):227-234.
8
9. Scott D, Evered L, Silbert B. Cardiac surgery, the brain, and inflammation. J Extra Corpor Technol. 2014;46(1):15–22.
9
10. Abrahamov D, Levran O, Naparstek S, Refaeli Y, Kaptson S, Abu Salah M, et al. Blood-Brain Barrier Disruption After Cardiopulmonary Bypass: Diagnosis and Correlation to Cognition. Ann Thorac surgery 2017;104(1)161-9. 2017;104(1):161–9.
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11. Hassani E, Mahoori A, Noroozinia H, Mehdizadeh H, Sepasi N. Evaluation of risk factors for adverse neurologic outcome after cardiac surgery. Urmia Med J. 2010;21(2):249–53.
11
12. O’Neal JB, Billings FT, Liu X, Shotwell MS, Liang Y, Shah AS, et al. Risk factors for delirium after cardiac surgery: a historical cohort study outlining the influence of cardiopulmonary bypass. Can J Anesth. 2017;64(11):1129–37.
12
13. Ottens TH, Sauër AMC, Peelen LM, De Groot WJ, Buijsrogge MP, Bredée JJ, et al. Effects of dexamethasone on cognitive decline after cardiac surgery a randomized clinical trial. In: Anesthesiology [Internet]. Lippincott Williams and Wilkins; 2014 [cited 2021 Jan 1]. p. 492–500. Available from: http:..links.lww.com.ALN.B58
13
14. Heidar I, Dianati M, Mousavi G. Prevalence of delirium , its related factors and short-term outcomes in ICU wards of Kashan Shahid-Beheshti and Isfahan Kashani hospitals during Abstract : Background : Delirium is one of the most common problems in ICUs . This study was conducted to inve. Feyz, J Kashan Univ Med Sci. 2014;18(1):76–84.
14
15. Koga Y, Tsuruta R, Murata H, Al E. Reliability and validity assessment of the Japanese version of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). Intensive Crit Care Nurs. 4923;31(3):165–70.
15
16. Tao R, Wang X-W, Pang L-J, Cheng J, Wang Y-M, Gao G-Q, et al. Pharmacologic prevention of postoperative delirium after on-pump cardiac surgery. Medicine (Baltimore). 2018;97(43):e12771.
16
17. Clemmesen CG, Lunn TH, Kristensen MT, Palm H, Foss NB. Effect of a single pre-operative 125 mg dose of methylprednisolone on postoperative delirium in hip fracture patients; a randomised, double-blind, placebo-controlled trial. Anaesthesia. 2018;73(11):1353–60.
17
18.Dieleman JM, Van Dijk D. Corticosteroids for cardiac surgery: A summary of two large randomised trials. Netherlands J Crit Care. 2016;24(5):6–10.
18
19. Mardani D, Bigdelian H. The effect of dexamethasone prophylaxis on postoperative delirium after cardiac surgery: A randomized trial. J Res Med Sci. 2012;17(1 SPL.1):9–10.
19
20. Dehghani Sani F, Shakibapour N, Beigoli S, Sadeghian H, Hosainzadeh M, Chamani J. Changes in binding affinity between ofloxacin and calf thymus DNA in the presence of histone H1: spectroscopic and molecular modeling investigations. Journal of Luminescence. 2018; 203:599-608.
20
21. Poorzand, H., Alvandi Azari, M., Eshraghi, A., Alimi, H., Bigdelu, L., Emadzadeh, M. Evaluation of Left Atrial Strain Parameter in Coronary Artery Stenosis: A New Tool to Predict LCX Stenosis. Journal of Cardio-Thoracic Medicine, 2020; 8(4): 693-699
21
ORIGINAL_ARTICLE
Hypertension and Its Risk Factors in the Population Covered by Mashhad University of Medical Sciences
Introduction: Hypertension is recognized as one of the major causes of cardiovascular disease. The present study aimed to assess the relationship between hypertension and its risk factors in the population referring to comprehensive health care centers affiliated to Mashhad University of Medical Sciences. Materials and Methods: This case-control study was performed on the health assessment data of the population aged 30 years and above registered in the SINA system in 2017-2018. The present case-control study was conducted on 1500 cases who were selected by systematic random sampling and assigned to the case group (500 hypertensive patients) and control group (1000 subjects without a history of hypertension). Data were analyzed using SPSS software (version 22). A p-value less than 0.05 was considered statistically significant. Results: Based on the results, the risk factors for hypertension included settlement in urban areas (OR=2.914), body mass index≥ 25 (OR = 2.522), waist circumference˃90 (OR=2.409), sedentary lifestyle (OR=2.373), consumption of solid oil (OR=1.581), triglyceride level of ˃150 (OR=566), use of table salt (OR=1.547). On the other hand, the following were identified as protective factors against hypertension: hard labor jobs (OR=0.292), optimal physical activity (OR=0.421), and regular consumption of vitamin D (OR=0.625) (p <0.05). Conclusion: The results will not only provide a solid foundation on potency of risk factors and protective factors for hypertension but will also give an invaluable insight to the health planning programs. The reduced prevalence of hypertension can be planned for with the identification of related risk and protective factors.
https://jctm.mums.ac.ir/article_17423_c05cd4be923cdb6a3cc04118185ea7a1.pdf
2021-03-01
739
746
10.22038/jctm.2021.52881.1301
Hypertension
Relative frequency
Risk factors
Nasrin
Milani
nasrinmilani@gmail.com
1
Internal Medicine, Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
AUTHOR
Ehsan
Mosa Farkhani
farkhanye1@mums.ac.ir
2
Epidemiologist, Department of Epidemiology & Biostatistics, School of Health, Social Determinants of Health Research Center, Cancer Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
AUTHOR
Mohamad
Sajjadi-Manesh
sajjadimm1@mums.ac.ir
3
Family Medicine Specialist, Department of Family Medicine, Faculty of Medicine ,Mashhad University of Medical Sciences, Mashhad, Iran
AUTHOR
Ali
Taghipour
taghipoura@mums.ac.ir
4
Ph.D. in Epidemiology, Khorasan Razavi Province Health Center, Mashhad University of Medical Sciences, Mashhad, Iran
AUTHOR
Reza
Ahmadi
ahmadirz@mums.ac.ir
5
Department of Family Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
AUTHOR
Kazem
Saeedi
saeedikazem@gmail.com
6
Epidemiologist, Department of Epidemiology & Biostatistics, School of Health, Social Determinants of Health Research Center, Cancer Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
LEAD_AUTHOR
1. Poulter NR, Prabhakaran D, Caulfield M. Hypertension. The Lancet. 2015;386(9995):801-12.
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2. Harrison TR. Harrison's principle of internal medicine. 20 th Edition ed. Harrison TR eUSM-HCp.
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4. Lewington S, Clarke R, Qizilbash N, Peto R, Collins R. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet. 2002;360(9349):1903-13.
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5. Ibrahim MM, Damasceno A. Hypertension in developing countries. The Lancet. 2012;380(9841):611-9.
5
6. Ahmed A, Rahman M, Hasan R, Shima SA, Faruquee M, Islam T, et al. Hypertension and associated risk factors in some selected rural areas of Bangladesh. International journal of research in medical sciences. 2014;2(3):925.
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7. Do HT, Geleijnse JM, Le MB, Kok FJ, Feskens EJ. National prevalence and associated risk factors of hypertension and prehypertension among Vietnamese adults. American journal of hypertension. 2015;28(1):89-97.
7
8. Jolly SE, Koller KR, Metzger JS, Day GM, Silverman A, Hopkins SE, et al. Prevalence of hypertension and associated risk factors in Western Alaska native people: the Western Alaska tribal collaborative for health (WATCH) study. The Journal of Clinical Hypertension. 2015;17(10):812-8.
8
9. Joshi MD, Ayah R, Njau EK, Wanjiru R, Kayima JK, Njeru EK, et al. Prevalence of hypertension and associated cardiovascular risk factors in an urban slum in Nairobi, Kenya: a population-based survey. BMC public health. 2014;14(1):1177.
9
10. Kingue S, Ngoe CN, Menanga AP, Jingi AM, Noubiap JJN, Fesuh B, et al. Prevalence and risk factors of hypertension in urban areas of Cameroon: a nationwide population‐based cross‐sectional study. The Journal of Clinical Hypertension. 2015;17(10):819-24.
10
11. Liu F, Adi D, Xie X, Li X-M, Fu Z-Y, Shan C-F, et al. Prevalence of isolated diastolic hypertension and associated risk factors among different ethnicity groups in Xinjiang, China. PLoS One. 2015;10(12):e0145325.
11
12. Lloyd-Sherlock P, Beard J, Minicuci N, Ebrahim S, Chatterji S. Hypertension among older adults in low-and middle-income countries: prevalence, awareness and control. International journal of epidemiology. 2014;43(1):116-28.
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13. Pinto IC, Martins D. Prevalence and risk factors of arterial hypertension: A literature review. Journal of Cardiovascular Medicine andTherapeutics. 2017;1(2):1-7.
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14. Rodgers A, Lawes C, MacMahon S. Reducing the global burden of blood pressure-related cardiovascular disease. Journal of hypertension Supplement : official journal of the International Society of Hypertension. 2000;18(1):S3-6.
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15. Wyss F, Coca A, Lopez-Jaramillo P, Ponte-Negretti C, Wyss FS, Restrepo G, et al. Position statement of the Interamerican Society of Cardiology (IASC) on the current guidelines for the prevention, diagnosis and treatment of arterial hypertension 2017–2020. International Journal of Cardiology Hypertension. 2020;6:100041.
15
16. Ahmadi A, Hasanzadeh J, Rajaefard A. To Determine the Relative Factors on Hypertension in Kohrang, Chaharmahal & Bakhtiari Province, 2007 %J Iranian Journal of Epidemiology. 2008;4(2):19-25.
16
17. Li Y, Feng X, Zhang M, Zhou M, Wang N, Wang L. Clustering of cardiovascular behavioral risk factors and blood pressure among people diagnosed with hypertension: a nationally representative survey in China. Scientific reports. 2016;6(1):1-7.
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18. Khanal MK, Dhungana RR, Bhandari P, Gurung Y, Paudel K. Prevalence, associated factors, awareness, treatment, and control of hypertension: Findings from a cross sectional study conducted as a part of a community based intervention trial in Surkhet, Mid-western region of Nepal. PLoS One. 2017;12(10):e0185806.
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19. Singh S, Shankar R, Singh GP. Prevalence and Associated Risk Factors of Hypertension: A Cross-Sectional Study in Urban Varanasi. International Journal of Hypertension. 2017;2017:5491838.
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20. Kazemi T, Tavakoli T, Hajihosseini M, Yari E. Prevalence of Pre-hypertension and Risk Factors in an Iranian Population: East of Iran. International Cardiovascular Research Journal. 2018;12(1).
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21. Gholizadeh S, Moghimbeigi A, Poorolajal J, Khjeian M, Bahramian F. Study of risk factors affecting both hypertension and obesity outcome by using multivariate multilevel logistic regression models %J Iranian South Medical Journal. 2016;19(3):385-97.
21
22. Chethana K, Anusha T, Mane A, Prasad V, Sunkad V. Prevalence of hypertension and its risk factors among adults in urban field practice area NMC, Raichur, Karnataka, India. International Journal of Community Medicine and Public Health Int J Community Med Public Health. 2017;4(1):45-50.
22
23. Ingale AS, Dixit J. Prevalence of hypertension and its associated risk factors in adults: A unique study at field practice area of urban health training centre. International Journal Of Community Medicine And Public Health. 2017;4(2):572-81.
23
24. Yang L, Yan J, Tang X, Xu X, Yu W, Wu H. Prevalence, awareness, treatment, control and risk factors associated with hypertension among adults in southern China, 2013. PloS one. 2016;11(1):e0146181.
24
25. Ghorbani R, Eskandarian R, Malek M, Rashidipour a. Prevalence of hypertension among the adult population of semnan province. Iranian journal of endocrinology and metabolism (ijem). 2009;10(5 (sn 41)):495-503.
25
26. Chamani j. Energetic domains analysis of bovine α-lactalbumin upon interaction with copper and dodecyl trimethylammonium bromide. Journal of Molecular Structure. 2010;979(1-3):227-234.
26
27. Dehghani Sani F, Shakibapour N, Beigoli S, Sadeghian H, Hosainzadeh M, Chamani J. Changes in binding affinity between ofloxacin and calf thymus DNA in the presence of histone H1: spectroscopic and molecular modeling investigations. Journal of Luminescence. 2018;203:599-608.
27
28. Hejazi, S., Mozdourian, M. Statins and Pulmonary Hypertension in Chronic Obstructive Lung Disease. Journal of Cardio-Thoracic Medicine, 2020; 8(1): 565-570.
28
ORIGINAL_ARTICLE
Effects of Aerobic Training and Pumpkin Seed Extract Consumption on the Heart and Aorta Oxidative Stress Biomarkers: A Case of Rats Exposed With Arsenic
Introduction: It has beenproposed that regular aerobic exercisetraining and medicinal plants are able to reduce oxidative damage resulted from toxin metal poisoning such as arsenic which is a significant risk factor in the heart diseases. The purpose of this research is to evaluate the simultaneous effect of regular aerobic exercise training and pumpkin extract on oxidative stress of the heart and endothelial cells of the aorta in rats poisoned with arsenic. Materials and Methods: 56 male Wistar rats were divided into seven groups including TC (toxic control); AE (aerobic exercise training); TAP1 (toxic aerobic exercise training + 300 mg/kg/day pumpkin seed extract consumption); TAP2 (toxic aerobic exercise training + 600 mg/kg/day pumpkin seed extract consumption); TP1 (300 mg/kg/day toxic pumpkin seed extract consumption); TP2 (600 mg/kg/day toxic pumpkin seed extract consumption), and HC (healthy control). The intervention was performed based on the groups' categorization. 24 hours after the last intervention the samples were collected. Statistical analyses were performed using one and two-way analysis of variance (ANOVA). Results: The results showed that exercise training increased GSH (p= 0.0001) and GSSG (p= 0.0001) and declined MDA levels (p= 0.0001) in the aortic endothelial cells and heart tissue. Also, pumpkin seed extract consumption induced a significant increase in GSH (p= 0.0001) and GSSG (p= 0.0001) and decreased MDA levels (p= 0.0001) in the aortic endothelial cells and heart. On the other hand, interaction of exercise training and pumpkin seed extract consumption increased GSH (p= 0.0001) and GSSG (p= 0.0001) and decreased MDA levels (p= 0.0001) in the aortic endothelial cells and heart. Conclusion:It is concluded that concurrent of pumpkin seed extract consumption and aerobic exercise training could intensify mutual antioxidant effects in oxidative stresses such as cardiac disorders caused by arsenic poisoning.
https://jctm.mums.ac.ir/article_17652_548fa5eadec4badfb8efad59de257f0e.pdf
2021-03-01
747
754
10.22038/jctm.2021.55557.1315
Endothelial Cells Glutathione
Malondialdehyde Glutathione-Disulfide
regular aerobic exercise
Oxidative Damage
Mahdi
Badkoobeh Hezaveh
m_badkoobe@yahoo.com
1
Department of Exercise Physiology, Mahallat Branch, Islamic Azad University, Mahallat, Iran.
AUTHOR
Bahram
Abedi
abedi@iaumahallat.ac.ir
2
Department of Exercise Physiology, Mahallat Branch, Islamic Azad University, Mahallat, Iran.
LEAD_AUTHOR
Saleh
Rahmati-Ahmadabad
salehrahmati@pardisiau.ac.ir
3
Department of Physical Education, Pardis Branch, Islamic Azad University, Pardis, Iran
AUTHOR
1. Chen C-J. Health hazards and mitigation of chronic poisoning from arsenic in drinking water: Taiwan experiences. Reviews on environmental health. 2014;29(1-2):13-9.
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2. Abdul KSM, Jayasinghe SS, Chandana EP, Jayasumana C, De Silva PMC. Arsenic and human health effects: A review. Environmental toxicology and pharmacology. 2015;40(3):828-46.
2
3. Nikkhoi SK, Heydarzadeh H, Ranjbar S, Salimi F, Aghaeifard M, Alavian SM, et al. The evaluation and comparison of transcriptionally targeted noxa and puma killer genes to initiate apoptosis under cancer-specific promoter cxcr1 in hepatocarcinoma gene therapy. Hepatitis monthly. 2016;16(10).
3
4. Saeidi, M., Komasi, S., Soroush, A., Zakiei, A., Shakeri, J. Gender Differences in Patients' Beliefs About Biological, Environmental, Behavioral, and Psychological Risk Factors in a Cardiac Rehabilitation Program. Journal of Cardio-Thoracic Medicine, 2014; 2(4): 215-220.
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5. Surai PF. Antioxidant systems in poultry biology: superoxide dismutase. Journal of Animal Research and Nutrition. 2016;1(1):8.
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6. Kaludercic N, Di Lisa F. Mitochondrial ROS formation in the pathogenesis of diabetic cardiomyopathy. Frontiers in Cardiovascular Medicine. 2020;7:12.
6
7. Karoui A, Crochemore C, Harouki N, Corbière C, Preterre D, Vendeville C, et al. Nitrogen Dioxide Inhalation Exposures Induce Cardiac Mitochondrial Reactive Oxygen Species Production, Impair Mitochondrial Function and Promote Coronary Endothelial Dysfunction. International Journal of Environmental Research and Public Health. 2020;17(15):5526.
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8. Poljsak B, Šuput D, Milisav I. Achieving the balance between ROS and antioxidants: when to use the synthetic antioxidants. Oxidative medicine and cellular longevity. 2013;2013.
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9. Roque FR, Briones AM, García‐Redondo AB, Galán M, Martínez‐Revelles S, Avendaño MS, et al. Aerobic exercise reduces oxidative stress and improves vascular changes of small mesenteric and coronary arteries in hypertension. British journal of pharmacology. 2013;168(3):686-703.
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10. Cunha TF, Bacurau AVN, Moreira JBN, Paixão NA, Campos JC, Ferreira JCB, et al. Exercise training prevents oxidative stress and ubiquitin-proteasome system overactivity and reverse skeletal muscle atrophy in heart failure. PloS one. 2012;7(8):e41701.
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11. Agati G, Azzarello E, Pollastri S, Tattini M. Flavonoids as antioxidants in plants: location and functional significance. Plant science. 2012;196:67-76.
11
12. Asif M, Raza Naqvi SA, Sherazi TA, Ahmad M, Zahoor AF, Shahzad SA, et al. Antioxidant, antibacterial and antiproliferative activities of pumpkin (cucurbit) peel and puree extracts-an in vitro study. Pakistan journal of pharmaceutical sciences. 2017;30(4).
12
13. Chamani j. Energetic domains analysis of bovine α-lactalbumin upon interaction with copper and dodecyl trimethylammonium bromide. Journal of Molecular Structure. 2010;979(1-3):227-234.
13
14. Seif HSA. Ameliorative effect of pumpkin oil (Cucurbita pepo L.) against alcohol-induced hepatotoxicity and oxidative stress in albino rats. Beni-Suef University Journal of Basic and Applied Sciences. 2014;3(3):178-85.
14
15. Kannan GM, Tripathi N, Dube SN, Gupta M, Flora S, Flora SJ. Toxic effects of arsenic (III) on some hematopoietic and central nervous system variables in rats and guinea pigs. Journal of Toxicology: Clinical Toxicology. 2001;39(7):675-82.
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16. Abbassi-Daloii A, Abdi A, Yazdani-Tapesari H, Salehpour M, Rostami-Angasi Z, Yahyaei B. Effect of 8 weeks aerobic training on plasma apelin in male rats treated with L-NAME. KAUMS Journal (FEYZ). 2016;20(2):118-24.
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17. Papastergiadis A, Mubiru E, Van Langenhove H, De Meulenaer B. Malondialdehyde measurement in oxidized foods: evaluation of the spectrophotometric thiobarbituric acid reactive substances (TBARS) test in various foods. Journal of agricultural and food chemistry. 2012;60(38):9589-94.
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18. Dannenmann B, Lehle S, Hildebrand DG, Kübler A, Grondona P, Schmid V, et al. High glutathione and glutathione peroxidase-2 levels mediate cell-type-specific DNA damage protection in human induced pluripotent stem cells. Stem Cell Reports. 2015;4(5):886-98.
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19. Sarkar A, Paul B. The global menace of arsenic and its conventional remediation-A critical review. Chemosphere. 2016;158:37-49.
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20. Siti HN, Kamisah Y, Kamsiah J. The role of oxidative stress, antioxidants and vascular inflammation in cardiovascular disease (a review). Vascular pharmacology. 2015;71:40-56.
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21. Bugger H, Pfeil K. Mitochondrial ROS in myocardial ischemia reperfusion and remodeling. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease. 2020;1866(7):165768.
21
22. Beigoli S, Sharifi Rad A, Askari A, Assaran Darban R, Chamani J. Isothermal titration calorimetry and stopped flow circular dichroism investigations of the interaction between lomefloxacin and human serum albumin in the presence of amino acids. Journal of Biomolecular Structure and Dynamics. 2019 Jun 13;37(9):2265-82.
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23. Hayes SM, Alosco ML, Forman DE. The effects of aerobic exercise on cognitive and neural decline in aging and cardiovascular disease. Current geriatrics reports. 2014;3(4):282-90.
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24. Gielen S, Laughlin MH, O’Conner C, Duncker DJ. Exercise training in patients with heart disease: review of beneficial effects and clinical recommendations. Progress in cardiovascular diseases. 2015;57(4):347-55.
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25. Ho SS, Dhaliwal SS, Hills AP, Pal S. The effect of 12 weeks of aerobic, resistance or combination exercise training on cardiovascular risk factors in the overweight and obese in a randomized trial. BMC public health. 2012;12(1):704.
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26. Eleuteri E, Mezzani A, Di Stefano A, Vallese D, Gnemmi I, Delle Donne L, et al. Aerobic training and angiogenesis activation in patients with stable chronic heart failure: a preliminary report. Biomarkers. 2013;18(5):418-24.
26
27. Beigoli S, Sharifi Rad A, Askari A, Assaran Darban R, Chamani J. Isothermal titration calorimetry and stopped flow circular dichroism investigations of the interaction between lomefloxacin and human serum albumin in the presence of amino acids. Journal of Biomolecular Structure and Dynamics. 2019;37(9):2265-2282.
27
28. Kanter M, Aksu F, Takir M, Kostek O, Kanter B, Oymagil A. Effects of low intensity exercise against apoptosis and oxidative stress in Streptozotocin-induced diabetic rat heart. Experimental and Clinical Endocrinology & Diabetes. 2017;125(09):583-91.
28
29. Shabestari, M., Blanc, R., Baharvahdat, H., Dehganizadeh, H., Piotin, M. Cardiac Complication Following Subarachnoid Hemorrhage. Journal of Cardio-Thoracic Medicine, 2018; 6(3): 313-318
29
30. Badalzadeh R, Shaghaghi M, Mohammadi M, Dehghan G, Mohammadi Z. The effect of cinnamon extract and long-term aerobic training on heart function, biochemical alterations and lipid profile following exhaustive exercise in male rats. Advanced pharmaceutical bulletin. 2014;4(Suppl 2):515.
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31. Yoon G, Park S. Antioxidant action of soy isoflavones on oxidative stress and antioxidant enzyme activities in exercised rats. Nutrition research and practice. 2014;8(6):618-24.
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32. Rasolifoshazeh A, Abedi B, Matinhomaee H, Farzanegi P. The Effect of Aerobic Training and Tribulus terrestris Extract on Some Oxidative Stress Indices in the Heart Tissue of Male Wistar Rats Poisoned with Hydrogen Peroxide. Gene, Cell and Tissue.7(4).
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33. Tofighi A, Ebrahimi Kalan A, Jamali Qarakhanlou B. The effect of resveratrol supplementation and aerobic training on cardiac tissue alteration of rats with acute myocardial infarction. Iran J Physiol Pharmacol. 2017;1:211-21.
33
ORIGINAL_ARTICLE
The Association of Red Blood Cell Distribution Width with Secondary Infection and Prognosis in hospitalized patients with COVID -19 pneumonia
Introduction: Novel Coronavirus outbreak has posed a global threat. While the infection appears to be mild in most patients, considering its high rate of transmission, a large number of people are at risk of developing severe to critical illness in total which makes prognosis studies a priority.The aim of the present study was to evaluate red blood cell distribution width (RDW) as a predictive factor for diagnosing severe cases of coronavirus disease 2019 (COVID-19).Materials and Methods: A total number of 204 inpatients diagnosed with COVID-19 including 122 men and 82 women (Mean age: 58.83±15.93 years old) treated at Imam Reza Hospital, Mashhad, Iran were included in the study. Patients were divided into severe and moderate groups according to their clinical signs and examinations and pulmonary imaging features. Demographic Data, laboratory test results, treatments, patients’ complications and outcome were recorded. Mann-Whitney U test and spearman correlation coefficient (r) were performed to assess RDW correlation with severity and serious complications in patients including intensive care unit (ICU) admission, shock, secondary infections, intubation, length of hospitalization and death. Receiver operating characteristics (ROC) curves analysis was carried out to define the reliability of RDW as a predictive indicator in severe COVID-19.Results: The results showed statistical significant correlations between high levels of RDW and developing secondary infections and longer hospitalization (P values ≤0.001). The optimal cutoff for RDW to predict the length of hospitalization (≤ 7 days or more than 7 days) was estimated to be 14.65% with 94% sensitivity and 71.3% specificity. The area under curve was calculated to be 0.895 through Roc curve analysis.Conclusion: High predictive value of RDW, a routine blood test parameter, could be used in diagnosing COVID-19 patients at higher risk for developing secondary infections and longer hospital stay which in turn helps with better management of the disease.
https://jctm.mums.ac.ir/article_17509_1ea789b1ccfdacdec0d86d367778dbfc.pdf
2021-03-01
755
761
10.22038/jctm.2021.55515.1313
Coronavirus Disease-19
Prognosis
Secondary Infection
Red Blood Cell Distribution Width
Neda
Saeedian
saeediann12@gmail.com
1
Internal Medicine, Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran.
AUTHOR
Mohsen
Seddigh Shamsi
seddigh.m52@gmail.com
2
Department of Hematology Oncology, Mashhad University of Medical Science, Mashhad, Iran
AUTHOR
Shima
Nabavi
nabavis46@gmail.com
3
Internist, Department of Internal Medicine, Mashhad University of Medical Science, Mashhad, Iran
AUTHOR
Zahra
Javidarabshahi
zahrajavidarabshahi14@gmail.com
4
Pulmonologist, Lung Diseases Research, Mashhad University of medical science, Mashhad, Iran
AUTHOR
Farnoosh
Ebrahimzadeh
farnooshebrahimzadeh25@gmail.com
5
Internist, Department of Internal Medicine, Mashhad University of Medical Science, Mashhad, Iran
AUTHOR
Sahar
Ravanshad
saharravanshad82@gmail.com
6
Department of Internal Medicine, Mashhad University of Medical Science, Mashhad, Iran
AUTHOR
Mina
Akbari Rad
minaakbarirad72@gmail.com
7
Internist, Department of Internal Medicine, Mashhad University of Medical Science, Mashhad, Iran
AUTHOR
Shohre
Khatami
shohrekhatami83@gmail.com
8
Internist, Department of Internal Medicine, Mashhad University of Medical Science, Mashhad, Iran
AUTHOR
Maryam
Emadzadeh
emadzadehm@mums.ac.ir
9
Clinical Research Unit, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
AUTHOR
Shaghayegh
Badriahmadi
shaghayeghbadriahmadi12@gmail.com
10
Internal Medicine, Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran.
AUTHOR
Mahnaz
Mozdourian
mozdorianmh@mums.ac.ir
11
Pulmonologist, Lung Diseases Research Center, Mashhad University of Medical Science, Mashhad, Iran
LEAD_AUTHOR
1. Yin Y, Wunderink RG. MERS, SARS and other coronaviruses as causes of pneumonia. Respirology. 2018;23(2):130-7.
1
2. Drosten C, Günther S, Preiser W, Van Der Werf S, Brodt H-R, Becker S, et al. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. New England journal of medicine. 2003;348(20):1967-76.
2
3. Zaki AM, Van Boheemen S, Bestebroer TM, Osterhaus AD, Fouchier RA. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. New England Journal of Medicine. 2012;367(19):1814-20.
3
4. Attaran, D., Ataei Azimi, S., M.Lari, S., Rokni, H., Taghavi, M., Maraashi, M. The Evaluation of Pulmonary Function Tests in Patients with Polycystic Ovary Syndrome. Journal of Cardio-Thoracic Medicine, 2013; 1(3): 84-88
4
5. Kuiken T, Fouchier RA, Schutten M, Rimmelzwaan GF, Van Amerongen G, van Riel D, et al. Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome. The Lancet. 2003;362(9380):263-70.
5
6. de Groot RJ, Baker SC, Baric RS, Brown CS, Drosten C, Enjuanes L, et al. Commentary: Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group. Journal of virology. 2013;87(14):7790-2.
6
7. Qu R, Ling Y, Zhang Yh, Wei Ly, Chen X, Li X, et al. Platelet‐to‐lymphocyte ratio is associated with prognosis in patients with Corona Virus Disease‐19. Journal of Medical Virology. 2020.
7
8. Beigoli S, Sharifi Rad A, Askari A, Assaran Darban R, Chamani J. Isothermal titration calorimetry and stopped flow circular dichroism investigations of the interaction between lomefloxacin and human serum albumin in the presence of amino acids. 2019;37(9):2265-2282.
8
9. Lu R, Zhao X, Li J, Niu P, Yang B, Wu H, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. The Lancet. 2020;395(10224):565-74.
9
10. Phelan A, Katz R, Gostin L. The novel coronavirus originating in wuhan. China, J Am Med Assoc. 2020.
10
11. Gorbalenya A, Baker S, Baric R. Severe acute respiratory syndrome-related coronavirus: the species and its viruses–a statement of the coronavirus study group. bioRxiv preprint first posted online February 11, 2020. 2020: 2020.2002. 2007.937862. doi: 10.1101/2020.02. 07.937862. Accessed February. 2020;12.
11
12. Holshue ML, DeBolt C, Lindquist S, Lofy KH, Wiesman J, Bruce H, et al. First case of 2019 novel coronavirus in the United States. New England Journal of Medicine. 2020.
12
13. Chamani j. Energetic domains analysis of bovine α-lactalbumin upon interaction with copper and dodecyl trimethylammonium bromide. Journal of Molecular Structure. 2010;979(1-3):227-234.
13
14. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet. 2020.
14
15. Feng Z, Yu Q, Yao S, Luo L, Duan J, Yan Z, et al. Early Prediction of Disease Progression in 2019 Novel Coronavirus Pneumonia Patients Outside Wuhan with CT and Clinical Characteristics. medRxiv. 2020.
15
16. Guan W-j, Chen R-c, Zhong N-s. Strategies for the prevention and management of coronavirus disease 2019. Eur Respiratory Soc; 2020.
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17. Coronavirus disease 2019 (COVID-19) Situation Report – 87 2020 [Available from: https://www.who.int/
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18. Guan W-j, Ni Z-y, Hu Y, Liang W-h, Ou C-q, He J-x, et al. Clinical characteristics of 2019 novel coronavirus infection in China. MedRxiv. 2020.
18
19. Gong J, Ou J, Qiu X, Jie Y, Chen Y, Yuan L, et al. A Tool to Early Predict Severe 2019-Novel Coronavirus Pneumonia (COVID-19): A Multicenter Study using the Risk Nomogram in Wuhan and Guangdong, China. medRxiv. 2020.
19
20. Liu J, Liu Y, Xiang P, Pu L, Xiong H, Li C, et al. Neutrophil-to-lymphocyte ratio predicts severe illness patients with 2019 novel coronavirus in the early stage. MedRxiv. 2020.
20
21. de Gonzalo-Calvo D, de Luxán-Delgado B, Rodríguez-González S, García-Macia M, Suárez FM, Solano JJ, et al. Interleukin 6, soluble tumor necrosis factor receptor I and red blood cell distribution width as biological markers of functional dependence in an elderly population: a translational approach. Cytokine. 2012;58(2):193-8.
21
22. Arbel Y, Weitzman D, Raz R, Steinvil A, Zeltser D, Berliner S, et al. Red blood cell distribution width and the risk of cardiovascular morbidity and all-cause mortality. Thrombosis and haemostasis. 2014;112(02):300-7.
22
23. Oh HJ, Park JT, Kim J-K, Yoo DE, Kim SJ, Han SH, et al. Red blood cell distribution width is an independent predictor of mortality in acute kidney injury patients treated with continuous renal replacement therapy. Nephrology Dialysis Transplantation. 2012;27(2):589-94.
23
24. Engström G, Smith J, Persson M, Nilsson P, Melander O, Hedblad B. Red cell distribution width, haemoglobin A 1c and incidence of diabetes mellitus. Journal of internal medicine. 2014;276(2):174-83.
24
25. Koma Y, Onishi A, Matsuoka H, Oda N, Yokota N, Matsumoto Y, et al. Increased red blood cell distribution width associates with cancer stage and prognosis in patients with lung cancer. PloS one. 2013;8(11).
25
26. Ozgul G, Seyhan EC, Ozgul MA, Gunluoglu MZ. Red blood cell distribution width in patients with chronic obstructive pulmonary disease and healthy subjects. Archivos de Bronconeumología (English Edition). 2017;53(3):107-13.
26
27. Wang B, Gong Y, Ying B, Cheng B. Relation between red cell distribution width and mortality in critically ill patients with acute respiratory distress syndrome. BioMed research international. 2019;2019.
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28. Nishimoto N. Interleukin‐6 as a therapeutic target in candidate inflammatory diseases. Clinical Pharmacology & Therapeutics. 2010;87(4):483-7.
28
29. Mahindra A, Laubach J, Raje N, Munshi N, Richardson PG, Anderson K. Latest advances and current challenges in the treatment of multiple myeloma. Nature reviews Clinical oncology. 2012;9(3):135.
29
30. Bazick HS, Chang D, Mahadevappa K, Gibbons FK, Christopher KB. Red cell distribution width and all cause mortality in critically ill patients. Critical care medicine. 2011;39(8):1913.
30
31. Zhu M, Han M, Xiao X, Lu S, Guan Z, Song Y, et al. Dynamic Differences Of Red Cell Distribution Width Levels Contribute To The Differential Diagnosis Of Hepatitis B Virus-related Chronic Liver Diseases: A Case-control Study. International Journal of Medical Sciences. 2019;16(5):720.
31
32. Rezaeetalab, F., Mozdourian, M., Amini, M., Javidarabshahi, Z., Akbari, F. COVID-19: A New Virus as a Potential Rapidly Spreading in the Worldwide. Journal of Cardio-Thoracic Medicine, 2020; 8(1): 563-564
32
ORIGINAL_ARTICLE
Evaluation of the Effects of Letrozole in Combination with Neoadjuvant Chemotherapy on Clinical Response Rate of Breast Cancer
AbstractThis randomized clinical trial was aimed to assess the efficacy of neoadjuvant letrozole in combination with standard neoadjuvant chemotherapy regimen on clinical response rate of hormone receptor positive locally advanced breast cancer.In this randomized clinical study, 42 female patients, ≥ 18 years, with clinical stage IIB-IIIC (T1-4, N0-3, M0), pathologically proven hormone receptor positive and HER2 negative, invasive ductal carcinoma of breast, were randomly assigned to receive standard neoadjuvant chemotherapy alone (control group) or letrozole 2.5 mg/d (in association with goserlin in premenopausal patients) concurrent with standard neoadjuvant chemotherapy (study group). Standard neoadjuvant chemotherapy regimen has consisted of 4 cycles of doxorubicin (60mg/m2) and cyclophodphamide (600mg/m2), followed by 4 cycles of paclitaxel (175mg/m2) every two weeks.At the beginning of the study all patients underwent thorough exmination of breast mass and axillary lymph nudes by palpation and ultrasonography. At the end of the study response rates were also evaluated by palpation and ultrasonography and subsequently patients were referred for surgury. Pathologic response rates were also evaluated on surgical specimens. All of the clinical, ultrasonographic and pathologic examinations during the trial were performed by a single specialist. Finally all the data were analysed statistically.Overall clinical response rates in breast were 95.2%, in both study and control group. Overall clinical response rates in axilla were 80.9% and 76.2% in study and control group respectively. Similarly, overall radiologic complete response rates in breast and axilla were 95.2% and 76.2% respectively in both study and control group. Totally, the comparison of overall clinical and radiologic response rates in th breast and axilla, showed no significant difference between control and study group (p>0.05).The addition of letrozol to standard neoadjuvant chemotherapy regimen was not associated with higher clinical and radiologic response rates in patients with locally advanced hormon receptor positive breast cancer.Keywords: Neoadjuvant chemotherapy, Letrozole, Locally advanced breast cancer
https://jctm.mums.ac.ir/article_17646_893b3eacfa9f49740f8c318e373d3ef0.pdf
2021-03-01
762
768
10.22038/jctm.2021.55048.1309
Neoadjuvant chemotherapy
Letrozole
locally advanced breast cancer
Zahra
Mozahheb
mozahebz@gmail.com
1
Department of Medical Oncology and Hematology, Imam Reza Hospital, Mashhad, Iran.
AUTHOR
Abolghasem
Alahyari
allahyari.abolghasem@yahoo.com
2
Department of Medical Oncology and Hematology, Imam Reza Hospital, Mashhad, Iran.
AUTHOR
Seyyedeh Fatemeh
Seyyedi Khabbaz
beetaseyyedi@gmail.com
3
Department of Medical Oncology and Hematology, Imam Reza Hospital, Mashhad, Iran
LEAD_AUTHOR
Asieh Sadat
Fattahi
fattahima@mums.ac.ir
4
Minimally Invasive and Endoscopic Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
AUTHOR
Mona
Najaf Najafi
najafm@mums.ac.ir
5
Department of Statistics and Social Medicine, Imam Reza Hospital, Mashhad, Iran.
AUTHOR
1. Winer EP. Malignant tumors of the breast. Cancer: principles and practice of oncology. 2001:1651-717.
1
2. Klein J, Tran W, Watkins E, Vesprini D, Wright FC, Hong NJ, Ghandi S, Kiss A, Czarnota GJ. Locally advanced breast cancer treated with neoadjuvant chemotherapy and adjuvant radiotherapy: a retrospective cohort analysis. BMC cancer. 2019 Dec 1;19(1):306.
2
3. Sinn HP, Helmchen B, Wittekind CH. TNM classification of breast cancer: changes and comments on the 7th edition. Der Pathologe. 2010 Sep 1;31(5):361-6.
3
4. Garg PK, Prakash G. Current definition of locally advanced breast cancer. Current Oncology. 2015 Oct;22(5):e409.
4
5. Bardia A, Dixon JM. Neoadjuvant therapy for newly diagnosed hormone-positive breast cancer. UpToDate. Waltham, MA: Wolters Kluwer. 2016.
5
6. Wolff AC, Hammond ME, Schwartz JN, Hagerty KL, Allred DC, Cote RJ, Dowsett M, Fitzgibbons PL, Hanna WM, Langer A, McShane LM. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. Archives of pathology & laboratory medicine. 2007 Jan;131(1):18-43.
6
7. Housaindokht MR, Chamani J, Saboury AA, Moosavi-Movahedi AA, Bahrololoom M. Three binding sets analysis of alpha-Lactalbumin by interaction of tetradecyl trimethyl ammonium bromide. Bulletin-Korean Chemical Society. 2001;22(2):145-148.
7
8. Sharifi-Rad A, Mehrzad J, Darroudi M, Saberi MR, Chamani J. Oil-in-water nanoemulsions comprising Berberine in olive oil: biological activities, binding mechanisms to human serum albumin or holo-transferrin and QMMD simulations. Journal of Biomolecular Structure and Dynamics. 2021;39(3):1029-1043.
8
9. Eisenhauer EA, Therasse P, Bogaerts J, Schwartz LH, Sargent D, Ford R, Dancey J, Arbuck S, Gwyther S, Mooney M, Rubinstein L. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). European Journal of Cancer. 2009 Jan 1;45(2):228-47.
9
10. Schick P, Goodstein J, Moor J, Butler J, Senter KL. Preoperative chemotherapy followed by mastectomy for locally advanced breast cancer. Journal of surgical oncology. 1983 Apr;22(4):278-82.
10
11. Torrisi R, Bagnardi V, Rotmensz N, Scarano E, Iorfida M, Veronesi P, Luini A, Viale G, Santoro A, Colleoni M, Goldhirsch A. Letrozole plus GnRH analogue as preoperative and adjuvant therapy in premenopausal women with ER positive locally advanced breast cancer. Breast cancer research and treatment. 2011 Apr;126(2):431-41.
11
12. Mohammadianpanah M, Ashouri Y, Hoseini S, Amadloo N, Talei A, Tahmasebi S, Nasrolahi H, Mosalaei A, Omidvari S, Ansari M, Mosleh-Shirazi MA. The efficacy and safety of neoadjuvant chemotherapy+/− letrozole in postmenopausal women with locally advanced breast cancer: a randomized phase III clinical trial. Breast cancer research and treatment. 2012 Apr;132(3):853-61.
12
13. Redden MH, Fuhrman GM. Neoadjuvant chemotherapy in the treatment of breast cancer. Surgical Clinics. 2013 Apr 1;93(2):493-9. M.
13
14. Lari, S., Attaran, D., RokniYazdi, H., Towhidi, M., Shadkam, O., Asadi, A., Khajehdaluee, M., Ayatollahi, H., Ghayour-Mobarhan, M. Metabolic Syndrome in Chemical Warfare Patients with Chronic Obstructive Pulmonary Disease. Journal of Cardio-Thoracic Medicine, 2014; 2(4): 231-237
14
ORIGINAL_ARTICLE
Emergency Surgical Repair of Post Infarction Ventricular Septal Rupture
Ventricular septal rupture (VSR) is a life-threatening complication of myocardial infarction (MI). Surgery remains the only option; however it is still a challenging (1). Patients survive following medical management have poor outcome, so, its result is disappointing (2). Primary percutaneous coronary intervention (PCI) can be reduced VSR incidence. Medical treatment has high mortality, and early surgery is recommended to prevent hemodynamic deterioration. However, surgery also associated to a high of mortality rate (3). Transcatheter device closure is an option in critical cases (4).
https://jctm.mums.ac.ir/article_17508_252da3f135a3473cfa001db10b0039a9.pdf
2021-03-01
769
772
10.22038/jctm.2021.55429.1310
Acute myocardial infarction
Ischemic Ventricular Septal Defect
Post Infarction Mechanical Complications
Ventricular Septal Rupture
Yasser
Mubarak
yassermubarak73@gmail.com
1
Thoracic Surgeon, Cardiothoracic Surgery Department, Faculty of Medicine, Minia University, Egypt. Madinah Cardiac Center, King Fahad Hospital, Madinah, KSA.
LEAD_AUTHOR
Furukawa K, Shirasaki Y, Ishii H, Nakamura E, Nakamura K. Extended sandwich technique via the right atrial approach for post-infarction posterior ventricular septal rupture. General thoracic and cardiovascular surgery. 2020 Jun;68(6):629-32.
1
2. Deja MA, Szostek J, Widenka K, Szafron B, Spyt TJ, Hickey MS, Sosnowski AW. Post infarction ventricular septal defect–can we do better?. European journal of cardio-thoracic surgery. 2000 Aug 1;18(2):194-201.
2
3. Labrousse L, Choukroun E, Chevalier JM, Madonna F, Robertie F, Merlico F, Coste P, Deville C. Surgery for post infarction ventricular septal defect (VSD): risk factors for hospital death and long term results. European journal of cardio-thoracic surgery. 2002 Apr 1;21(4):725-32.
3
4. Tanzadehpanah H, Asoodeh A, Saberi MR, Chamani J. Identification of a novel angiotensin-I converting enzyme inhibitory peptide from ostrich egg white and studying its interactions with the enzyme. Innovative Food Science & Emerging Technologies. 2013;18:212-219.
4
5. Poorzand, H., AlvandiAzari, M., Eshraghi, A., Alimi, H., Bigdelu, L., Emadzadeh, M. Evaluation of Left Atrial Strain Parameter in Coronary Artery Stenosis: A New Tool to Predict LCX Stenosis. Journal of Cardio-Thoracic Medicine, 2020; 8(4): 693-699
5
6. Barker TA, Ramnarine IR, Woo EB, Grayson AD, Au J, Fabri BM, Bridgewater B, Grotte GJ. Repair of post-infarct ventricular septal defect with or without coronary artery bypass grafting in the northwest of England: a 5-year multi-institutional experience. European journal of cardio-thoracic surgery. 2003 Dec 1;24(6):940-6.
6
7. Beigoli S, Sharifi Rad A, Askari A, Assaran Darban R, Chamani J. Isothermal titration calorimetry and stopped flow circular dichroism investigations of the interaction between lomefloxacin and human serum albumin in the presence of amino acids. Journal of Biomolecular Structure and Dynamics. 2019 Jun 13;37(9):2265-82.
7
8. Gilmanov D, Farneti P, Solinas M, Glauber M. Severe mitral regurgitation in patients with postinfarctioninterventricular septal defect: a simple way of simultaneous valve repair. European Journal of Cardio-Thoracic Surgery. 2013 Jan 1;43(1):184-6.
8
9. Apostolakis EE, Kallikourdis A, Baikoussis NG, Dedeilias P, Dougenis D. " The non-ischemic repair" as a safe alternative method for repair of anterior post-infarction VSD. Journal of cardiothoracic surgery. 2010 Dec;5(1):1-4.
9
ORIGINAL_ARTICLE
Rare Presentation of Sarcoidosis
Sarcoidosis is an idiopathic, noncaseating granulomatous disorder with wide systemic involvement. Lungs, eyes, and skin are the organs most commonly affected. Bone involvement, which is very rare, was reported as present in 3 to 13% of affected cases. Here we present a case of young female with ribs, vertebrae and pulmonary involvement, lesion mimicking as metastasis or tuberculosis thus emphasizing the importance of differential diagnosis.
https://jctm.mums.ac.ir/article_17510_4dc403162d0140cedebbb45274996c49.pdf
2021-03-01
773
776
10.22038/jctm.2021.53507.1306
Skeletal
Sarcoidosis
Metastasis
Vertebrae
Suchita
Pant
suchitapant22@gmail.com
1
Pulmonologist, Department of Pulmonary Medicine, HIMS, Jollygrant, Dehradun, Indian.
AUTHOR
Varuna
Jethani
varuna1212@rediffmail.com
2
Pulmonologist, Department of Pulmonary Medicine, HIMS, Jollygrant, Dehradun, Indian.
LEAD_AUTHOR
Smita
Chandra
smitachandra@srhu.edu.in
3
Pathologist, Department of Pathology, HIMS, Jollygrant, Dehradun, Indian
AUTHOR
Prachi
Kala
prachi_kala@yahoo.com
4
Radiologist, Department of Radiodiagnosis, HIMS, Jollygrant, Dehradun, Indian
AUTHOR
Kumar
Nishant
nishant.stylo@gmail.com
5
Pulmonologist, Department of Pulmonary Medicine, HIMS, Jollygrant, Dehradun, Indian.
AUTHOR
Shivam
Sinha
dr.shivam.sinha@gmail.com
6
Pulmonologist, Department of Pulmonary Medicine, HIMS, Jollygrant, Dehradun, Indian.
AUTHOR
Iannuzzi MC, Rybicki BA, Teirstein AS, Sarcoidosis N. Engl. J Med. 2007;357:2153-65.
1
Newman LS, Rose CS, Bresnitz EA, Rossman MD, Barnard J, Frederick M, Terrin ML, Weinberger SE, Moller DR, McLennan G, Hunninghake G. A case control etiologic study of sarcoidosis: environmental and occupational risk factors. American journal of respiratory and critical care medicine. 2004 Dec 15;170(12):1324-30.
2
O'Daly BJ, Harty JA, O'Malley N, Killeen R, McDonnell TJ, Quinlan WR. Bilateral olecranon fracture as first presentation of sarcoidosis: case report and review of the literature. Journal of shoulder and elbow surgery. 2008 Jul 1;17(4):e1-5.
3
Haddad N, Oliveira Filho JD, Nasser KD, Corbett AM, Tebet AC, Reis ML. Musculoskeletal and cutaneous sarcoidosis: exuberant case report. Anais brasileiros de dermatologia. 2014 Aug;89(4):660-2.
4
Greer EL, Banko MR, Brunet A. AMP-activated protein kinase and FoxO transcription factors in dietary restriction–induced longevity. Annals of the New York Academy of Sciences. 2009 Jul; 1170:688.
5
Packer CD, Mileti LM. Vertebral sarcoidosis mimicking lytic osseous metastases: development 16 years after apparent resolution of thoracic sarcoidosis. JCR: Journal of Clinical Rheumatology. 2005 Apr 1;11(2):105-8.
6
Sweiss NJ, Lower EE, Korsten P, Niewold TB, Favus MJ, Baughman RP. Bone health issues in sarcoidosis. Current rheumatology reports. 2011 Jun 1;13(3):265-72.
7
Salari M, Rezaieyazdi Z. Prevalence and clinical picture of musculoskeletal sarcoidosis. Iranian Red Crescent Medical Journal. 2014 Jul;16(7).
8
Delghandi, M., Rezaeetalab, F., Ebrahimzadeh, F., Najaf Najafi, M. Investigation serum procalcitonin in patients with exacerbation of obstructive pulmonary disease. Journal of Cardio-Thoracic Medicine, 2020; 8(4): 700-706.
9
Chamani J. Energetic domains analysis of bovine α-lactalbumin upon interaction with copper and dodecyl trimethylammonium bromide. Journal of Molecular Structure. 2010;979(1-3):227-234.
10
Gupta SK, Mitra K, Chatterjee S, Chakravarty SC. Sarcoidosis in India. Br J Dis Chest. 1985;79(C):275–83.
11
Sharma SK, Mohan A. Sarcoidosis in India: not so rare. Journal, Indian Academy of Clinical Medicine. 2004;5(1):12-21.
12
Mootha VK, Agarwal R, Aggarwal AN, Gupta D, Ahmed J, Verma I, Bal A. The Sarcoid–Tuberculosis link: evidence from a high TB prevalence country. Journal of Infection. 2010 Jun 1;60(6):501-3.
13
Kemah B, Özturan B, Bilgic B, Özkan K, Akpınar F, Kılıc B. An Unusual Orthopaedic Disease: Sarcoidosis—A Case Report. The Surgery Journal. 2017 Apr;3(2):e75.
14
Jansen TL, Geusens PP. Sarcoidosis: joint, muscle and bone involvement. European Respiratory Monograph. 2005 Sep 1;32:210.
15
ORIGINAL_ARTICLE
Combined Pulmonary Fibrosis and Emphysema: A Case Report and Literature Review
The syndrome of combined emphysema of the upper lobes and fibrosis of the lower lobes on chest computed tomography results in a characteristic functional profile, with preserved lung volumes, hypoxemia at exercise. Despite subnormal spirometry, combined pulmonary fibrosis and emphysema is a severe entity. The presence of pulmonary arterial hypertension at diagnosis is a critical determinant of prognosis.
https://jctm.mums.ac.ir/article_17632_b03274ed6714c365673483a2d9365919.pdf
2021-03-01
777
779
10.22038/jctm.2021.55771.1316
CPFE
Emphysema
Pulmonary Fibrosis
Shaghayegh
Badriahmadi
shaghayeghbadriahmadi12@gmail.com
1
Internal Medicine, Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran
AUTHOR
Mahnaz
Mozdourian
mozdorianmh@mums.ac.ir
2
Pulmonologist, Lung Diseases Research Center, Mashhad University of Medical Science, Mashhad, Iran.
LEAD_AUTHOR
1. Lin H, Jiang S. Combined pulmonary fibrosis and emphysema (CPFE): an entity different from emphysema or pulmonary fibrosis alone. Journal of thoracic disease. 2015;7(4):767.
1
2. Hasani, S., Mozdourian, M. Chronic obstructive pulmonary disease and bone health: A review on possible links and follow up studies. Journal of Cardio-Thoracic Medicine, 2020; 8(4): 684-692
2
3. Jankowich MD, Polsky M, Klein M, Rounds S. Heterogeneity in combined pulmonary fibrosis and emphysema. Respiration. 2008;75(4):411-7.
3
4. Cottin V, Brillet P-Y, Nunes H, Cordier J-F. Combined pulmonary fibrosis and emphysema. Presse medicale (Paris, France: 1983). 2007;36(6 Pt 2):936-44.
4
5. American Thoracic S. Chronic bronchitis, asthma, and pulmonary emphysema: a statement by the Committee on Diagnostic Standards for Nontuberculous Respiratory Diseases. Am Rev Respir Dis. 1962;85:762-28.
5
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8. Marten K, Milne D, Antoniou KM, Nicholson AG, Tennant RC, Hansel TT, et al. Non-specific interstitial pneumonia in cigarette smokers: a CT study. European radiology. 2009;19(7):1679-85.
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9. Cottin V, Cordier J-F. The syndrome of combined pulmonary fibrosis and emphysema. Chest. 2009;136(1):1-2.
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12. Hiwatari N, Shimura S, Takishima T. Pulmonary emphysema followed by pulmonary fibrosis of undetermined cause. Respiration. 1993;60(6):354-8.
12
13. Ryerson CJ, Hartman T, Elicker BM, Ley B, Lee JS, Abbritti M, et al. Clinical features and outcomes in combined pulmonary fibrosis and emphysema in idiopathic pulmonary fibrosis. Chest. 2013;144(1):234-40.
13
14. Cottin V, Nunes H, Brillet P, Delaval P, Devouassoux G, Tillie-Leblond I, et al. Combined pulmonary fibrosis and emphysema: a distinct underrecognised entity. European Respiratory Journal. 2005;26(4):586-93.
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15. Chamani J. Energetic domains analysis of bovine α-lactalbumin upon interaction with copper and dodecyl trimethylammonium bromide. Journal of Molecular Structure. 2010;979(1-3)227-234.
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1. Lin H, Jiang S. Combined pulmonary fibrosis and emphysema (CPFE): an entity different from emphysema or pulmonary fibrosis alone. Journal of thoracic disease. 2015;7(4):767.
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2. Hasani, S., Mozdourian, M. Chronic obstructive pulmonary disease and bone health: A review on possible links and follow up studies. Journal of Cardio-Thoracic Medicine, 2020; 8(4): 684-692
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3. Jankowich MD, Polsky M, Klein M, Rounds S. Heterogeneity in combined pulmonary fibrosis and emphysema. Respiration. 2008;75(4):411-7.
19
4. Cottin V, Brillet P-Y, Nunes H, Cordier J-F. Combined pulmonary fibrosis and emphysema. Presse medicale (Paris, France: 1983). 2007;36(6 Pt 2):936-44.
20
5. American Thoracic S. Chronic bronchitis, asthma, and pulmonary emphysema: a statement by the Committee on Diagnostic Standards for Nontuberculous Respiratory Diseases. Am Rev Respir Dis. 1962;85:762-28.
21
6. Katzenstein A-LA, Myers JL. Idiopathic pulmonary fibrosis: clinical relevance of pathologic classification. American journal of respiratory and critical care medicine. 1998;157(4):1301-15.
22
7. Jankowich MD, Rounds SIS. Combined pulmonary fibrosis and emphysema syndrome: a review. Chest. 2012;141(1):222-31.
23
8. Marten K, Milne D, Antoniou KM, Nicholson AG, Tennant RC, Hansel TT, et al. Non-specific interstitial pneumonia in cigarette smokers: a CT study. European radiology. 2009;19(7):1679-85.
24
9. Cottin V, Cordier J-F. The syndrome of combined pulmonary fibrosis and emphysema. Chest. 2009;136(1):1-2.
25
10. Kitaguchi Y, Fujimoto K, Hanaoka M, Kawakami S, Honda T, Kubo K. Clinical characteristics of combined pulmonary fibrosis and emphysema. Respirology. 2010;15(2):265-71.
26
11. Odani K, Yoriko M, Shoji Y. Computed tomographic evaluation in the cases of coexistence of pulmonary emphysema with idiopathic pulmonary fibrosis. Journal of Tomography (Japan). 2004;31(1):25-9.
27
12. Hiwatari N, Shimura S, Takishima T. Pulmonary emphysema followed by pulmonary fibrosis of undetermined cause. Respiration. 1993;60(6):354-8.
28
13. Ryerson CJ, Hartman T, Elicker BM, Ley B, Lee JS, Abbritti M, et al. Clinical features and outcomes in combined pulmonary fibrosis and emphysema in idiopathic pulmonary fibrosis. Chest. 2013;144(1):234-40.
29
14. Cottin V, Nunes H, Brillet P, Delaval P, Devouassoux G, Tillie-Leblond I, et al. Combined pulmonary fibrosis and emphysema: a distinct underrecognised entity. European Respiratory Journal. 2005;26(4):586-93.
30
15. Neghab M, Rahimi E, Emad A, Fard ARR. An epidemiological study of talc-related respiratory morbidity among employees of a rubber industry in Shiraz-Iran. International archives of occupational and environmental health. 2007;80(6):539-46.
31