Mashhad University of Medical Sciences
Journal of Cardio-Thoracic Medicine
2345-2447
2322-5750
9
3
2021
09
01
The Effect of Curcumin on HDL Cholesterol Uptake Capacity in Obese Individuals: A Pilot Study
833
838
EN
Maryam
Saberi-Karimian
0000-0003-2314-0471
Lung Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
saberikm@mums.ac.ir
Mina
Nosrati
International UNESCO center for Health Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran
minanosrati064@gmail.com
Arezoo
Orooji
Student Research Committee, Department of Epidemiology and Biostatistics, Faculty of Health, Mashhad University of Medical Sciences, Mashhad, Iran.
arezoo.orooji23@gmail.com
Tooba
Kazemi
Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran
drtooba.kazemi@gmail.com
Ali
Javandoost
International UNESCO center for Health Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran
javandoosta1@mums.ac.ir
Akram
Mohammadi
International UNESCO center for Health Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran
mohammadia1@mums.ac.ir
Gordon A.
Ferns
0000-0002-0957-8349
Brighton & Sussex Medical School, Division of Medical Education, Falmer, Brighton, Sussex BN1 9PH, UK.
g.ferns@bsms.ac.uk
Malihe
Aghasizadeh
0000-0000-0000-0000
Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran
maliagh20@gmail.com
Majid
Ghayour-Mobarhan
0000-0002-1081-6754
International UNESCO center for Health Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran
ghayourm@mums.ac.ir
10.22038/jctm.2021.58306.1336
<strong>Introduction: </strong>Obesity is a common risk factor associated with cardiovascular disease (CVD) risk. Curcumin has been reported to exert beneficial effects on lipid metabolism, including HDL functionality. We have examined the effects of curcumin on HDL cholesterol uptake capacity in subjects with obesity.<br /><strong>Materials and Methods: </strong>30 obese individuals received curcumin and placebo 1 g per day for a period of 30 days. The subjects were crossed over to the alternative regimen after a 2-week washout period. A modified cholesterol uptake capacity (CUC) assay was used to determine serum HDL functionality.<br /><strong>Results: </strong>The study groups had similar base line characteristics. We did not find significant effects (p>0.05) of curcumin on serum HDL CUC levels.<br /><strong>Conclusion:</strong> Curcumin administration at a dose of 1 g per day for 30 days did not affect HDL CUC in subjects with obesity.
Curcuma longa,Curcumin,Cholesterol Uptake Capacity,metabolic syndrome
https://jctm.mums.ac.ir/article_18184.html
https://jctm.mums.ac.ir/article_18184_2fd8193936974a19e0e07fa78cfc6daf.pdf
Mashhad University of Medical Sciences
Journal of Cardio-Thoracic Medicine
2345-2447
2322-5750
9
3
2021
09
01
Cardiac Rehabilitation and Secondary Prevention Program effect in Chronic Total Occlusion Percutaneous Coronary Intervention patients
839
844
EN
Lara
Vargas
Jorge Antonio
0000 0002 6383 9859
Cardiac Rehabilitation and Nuclear Medicine Departments. NMC 20 de Noviembre, México City, México.
ikcaban@yahoo.com.mx
Tomas
Hernández-Esparza
Cardiac Rehabilitation and Nuclear Medicine Departments. NMC 20 de Noviembre, México City, México.
tomyhernandez20@hotmail.com
Adriana
Puente-Barragán
Cardiac Rehabilitation and Nuclear Medicine Departments. NMC 20 de Noviembre, México City, México.
adripuente@yahoo.com
Julieta
Morales- Portano
Cardiac Rehabilitation and Nuclear Medicine Departments. NMC 20 de Noviembre, México City, México.
mdanira@hotmail.com
Enrique
Gómez-Álvarez
Cardiac Rehabilitation and Nuclear Medicine Departments. NMC 20 de Noviembre, México City, México.
egomezal@hotmail.com
Jose
Alfredo
Merino-Rajmé
Cardiac Rehabilitation and Nuclear Medicine Departments. NMC 20 de Noviembre, México City, México.
alfredo.merino@issste.gob.mx
Eduardo
Leyva-Valadez
Cardiac Rehabilitation and Nuclear Medicine Departments. NMC 20 de Noviembre, México City, México.
eduardo.leyva.ft@hotmail.com
Jose
Luis
Aceves-Chimal
0000 0003 0578 4935
Cardiac Rehabilitation and Nuclear Medicine Departments. NMC 20 de Noviembre, México City, México.
aceves996@hotmail.com
10.22038/jctm.2021.57183.1326
<strong>Introduction:</strong> Chronic Total Coronary Occlusion has a high risk of mortality associated with Acute Coronary Syndrome with significantly ventricular disfunction reflected in functional class patient by intolerance to perform physical effort. The Percutaneous Coronary Intervention is the gold standard approach, but in many patients this procedure is not successful. Cardiac Rehabilitation and Secondary Prevention Programs has showed improve the patient's ability to perform physical effort by its positive effect on endothelial function and promote angiogenesis, increasing the ischemic threshold. We evaluate the Cardiac Rehabilitation and Secondary Prevention program effect on myocardial performance and ischemic profile in successful and unsuccessful Chronic Total Occlusion Percutaneous Coronary Intervention patients.<br /><strong>Materials and Methods. </strong>A non-randomized clinical trial was conducted in patients with CTCO underwent to Percutaneous Coronary Intervention (PCI). Patients were divided into two groups: 1) With successful PCI and 2) With unsuccessful PCI. All patients underwent a Sestamibi-Dipyridamole cardiac scan and stress test before and after of CRH&SP. The cardiac rehabilitation program considered 4-6 weeks of 5 weekly 30-minute training sessions with aerobic at 70% of Heart Resistance Reserve (HRR), with interspersed 3 weekly strength training sessions, as well as nutritional and Psychiatric group interventions.<br /><strong>Results. </strong>We evaluated 25 patients with successful PCI (n = 13) and unsuccessful PCI (n = 12). For both groups, the CRH&SP showed significant improvement (p <0.05) in myocardial performance parameters, ischemic profile, and physical effort tolerance, with a Cohen's Delta ≥ 80% in Nuclear Medicine Risk, NYHA functional class, METs reached, oxygen consumption, Myocardial Efficacy Index and Duke Score.<br /><strong>Conclusions. </strong>The CRH&SP has a high positive effect on ventricular function improvement, myocardial performance, and ischemic profile in patients with Chronic Total Coronary Occlusion<strong>.</strong>
Chronic Total Occlusion,Secondary Prevention,Percutaneous Coronary,Interventionism
https://jctm.mums.ac.ir/article_18414.html
https://jctm.mums.ac.ir/article_18414_fb32900c7564abd15d2d4920b81f96a3.pdf
Mashhad University of Medical Sciences
Journal of Cardio-Thoracic Medicine
2345-2447
2322-5750
9
3
2021
09
01
Correlation of spirometry Parameters and Clinical Variables among Post Extubated Patients in Selected Intensive Care Unit of Tertiary Care Hospital
845
853
EN
Drishti
Khugshal
0000-0003-1870-1545
Nurse practitioner, Swami Rama Himalayan University, Dehradun, India
drishti.khugshal@gmail.com
Rajesh
Kumar Sharma
Himalayan College of Nursing, Dehradun, India
rksharma@srhu.edu.in
Sushant
Khanduri
0000-0002-4877-860X
Pulmonary medicine, Department of Pulmonary Medicine, Swami Rama Himalayan University, Dehradun, India
sushant.khanduri@gmail.com
Sanchita
Pugazhendi
Department of Nursing, Swami Rama Himalayan University, Dehradun, India
sanchitapugazhendi13@gmail.com
Rakhee
Sodhi Khanduri
0000-0003-4691-3457
Department of Respiratory Medicine, Swami Rama Himalayan University, Dehradun, India
rakhee.sodhi@gmail.com
10.22038/jctm.2021.58285.1335
<strong>Introduction:</strong> Intubation is the common medical procedure which involves the insertion of a plastic tube which is a flexible tube in the throat of the patient. Reintubation is described as the failed extubation or patient get intubation after extubation who had been initially tracheal intubated.The purpose of the study was to determine the Spiro metric parameters among post Extubated patients and the application of Non-Invasive Ventilation for - prevention of reintubation.<br /><strong>Materials and Method: </strong>Quantitative research approach with purposive sampling technique was adopted to include 38 participants. Data were collected by providing spirometry immediately after extubation. The data were analyzed using descriptive statistics.<br /><strong>Results: </strong>The result shows that 36.84% of participants required non-invasive ventilation after extubation who were having FEV1 between 0.38-1.48, FVC between 0.44-1.75, PEFR between50-70. Hemodynamic variable like saturation (0.01), PCO2 (0.00), PO2 (0.03), and HCO3 (0.00) were highly significant at the level of p < 0.05. Proving that patients whose saturation level& ABG profile like PCO2, PO2, and HCO3 are not maintained required NIV after extubation.<br /><strong>Conclusion: </strong>Study concludes that in Extubated patient’s prophylactic non-invasive ventilation prevents extubation failure assessing the Spiro metric parameters in patients who can maintain saturation with less oxygen support, is also important in predicting good outcome of non-invasive ventilation after extubation.
Clinical variables,Post - Extubated Patients,Non-invasive Ventilation,Spontaneous Breathing Trial,Spirometric parameters
https://jctm.mums.ac.ir/article_18757.html
https://jctm.mums.ac.ir/article_18757_b496066c1e6315e2f434b48fcf708b5a.pdf
Mashhad University of Medical Sciences
Journal of Cardio-Thoracic Medicine
2345-2447
2322-5750
9
3
2021
09
01
Acute Severe Mitral Regurgitation due to Papillary Muscle Rupture after Blunt Chest Trauma: Case Report
854
857
EN
Yasser
Shaban
Mubarak
0000-0001-8460-2778
Thoracic Surgeon, Cardiothoracic Surgery Department, Faculty of Medicine, Minia University, Egypt. Madinah Cardiac Center, King Fahad Hospital, Madinah, KSA.
yassermubarak73@gmail.com
10.22038/jctm.2021.56406.1319
Cardiac injury is a common unexpected injury with high rate of mortality in multi-trauma patients. Blunt thoracic trauma leading to heart injury presented with variable presentations from myocardial contusion to rupture. Cardiac injury is about 15% - 25% of blunt chest trauma. Cardiac contusion is the most common type of injury with variable manifestations associated with electrocardiogram <em>(ECG)</em> changes or cardiac enzyme abnormality. Traumatic rupture of intra-cardiac structures after blunt Thoracic trauma is an uncommon. Cardiac valves rupture is uncommon, and the most frequent being aortic valve, and then followed by mitral and tricuspid. Nowadays, the incidence of these types of injury is increasing due to high increase of road traffic accidents <em>(RTA)</em>. Following blunt thoracic trauma, rupture of papillary muscle or its chordae tendineae is a very rare causing acute mitral regurgitation <em>(MR</em>) with sequence of congestive heart failure <em>(HF)</em> and pulmonary edema.
Acute Mitral Regurgitation,Blunt chest trauma,Papillary muscle rupture
https://jctm.mums.ac.ir/article_17960.html
https://jctm.mums.ac.ir/article_17960_aa6ee137a57928044d47ca02fb18b840.pdf
Mashhad University of Medical Sciences
Journal of Cardio-Thoracic Medicine
2345-2447
2322-5750
9
3
2021
09
01
Dramatic Improvement of Adult Patients with Post Tuberculosis Pulmonary Pneumatocele and Bad Pulmonary Function after Surgical Intervention.
858
862
EN
Yasser
Shaban
Mubarak
0000-0001-8460-2778
Thoracic Surgeon, Cardiothoracic Surgery Department, Faculty of Medicine, Minia University, Egypt. Madinah Cardiac Center, King Fahad Hospital, Madinah, KSA.
yassermubarak73@gmail.com
10.22038/jctm.2021.55436.1311
Pulmonary pneumatoceles (PCs) are thin-walled, air-filled cysts that develop within pulmonary parenchyma. PCs are usually seen in the lung after infection, trauma. In case of infection, as a complication of acute pneumonia, caused by Staphylococcus aureus, and are more frequently in infants and children. Adult tuberculous pulmonary pneumatoceles are seldom reported. PCs are usually asymptomatic. Large PCs may compress adjacent lung with mediastinal shift causing respiratory or cardiovascular symptoms. Surgical intervention is only indicated when PCs cause cardiopulmonary compromise or rupture into the pleural space or unresolved infection.
pulmonary pneumatocele,pulmonary tuberculosis,Fungal Ball,Cardiopulmonary Compromise
https://jctm.mums.ac.ir/article_17679.html
https://jctm.mums.ac.ir/article_17679_de7142173f5da8e906136f2e45437422.pdf
Mashhad University of Medical Sciences
Journal of Cardio-Thoracic Medicine
2345-2447
2322-5750
9
3
2021
09
01
Traumatic extracranial internal carotid-jugular fistula leading to serious injury: a case report in forensic assessment
863
866
EN
Shirin
Saberianpour
0000-0001-6805-8645
Vascular and Endovascular Surgery Research Center, Mashhad medical university, Mashhad, Iran
saberianpoursh@mums.ac.ir
Jamal
Jalili Shahri
0000-0002-2724-7463
Vascular and Endovascular Surgery Research Center, Mashhad medical university, Mashhad, Iran
jalilisj@mums.ac.ir
Mohammad Hossein
Hassani
Vascular and Endovascular Surgery Research Center, Mashhad medical university, Mashhad, Iran
hassanimh@mums.ac.ir
Ramin
Aghsaee
Vascular and Endovascular Surgery Research Center, Mashhad medical university, Mashhad, Iran
aghsaeer@mums.ac.ir
10.22038/jctm.2021.59148.1345
Traumatic carotid artery jugular vein fistula is a rare entity that is not usually detected during the acute injury phase. We presented 1 cases of traumatic carotid–jugular fistula. A 52 years old man that was referred to us because of an expanding neck hematoma. There was a 1×1 cm ulcer with a clot in zone II right neck and a thrill was palpated. We clamped the proximal and distal site of injury (Arteriovenous fistula), then divided the fistula and primarily repaired the artery (transversely) and the vein with 7-0 prolene suture. We placed two hemovac drains and then repaired the subcutaneous and skin and covered the site with gauze and then the patient was transferred to ICU. He was extubated the next day and physical exam was completely normal without any neurologic deficit. Carotid–jugular fistula should always be treated early to avoid the complications associated with the injury.
carotid,fistula,Traumatic,jugular
https://jctm.mums.ac.ir/article_18677.html
https://jctm.mums.ac.ir/article_18677_9c0864408b3b55c5a4fb70b655d575a0.pdf
Mashhad University of Medical Sciences
Journal of Cardio-Thoracic Medicine
2345-2447
2322-5750
9
3
2021
09
01
Chondroblastic Osteosarcoma of the Clavicle: A Case Report
867
868
EN
Reza
Bagheri
0000-0002-6785-1016
Lung Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
bagherir@mums.ac.ir
Maryam
Saberi-Karimian
0000-0003-2314-0471
Lung Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
saberikm@mums.ac.ir
10.22038/jctm.2021.58362.1337
In current observational study, we have reported a patient with Iraqi nationality suffering from chondroblastic osteosarcoma of the clavicle (Figure 1). He aged 17 years old having height 1.75 cm and weight 60 kg without any family history of malignancy. The signs have been started 1 year ago as a painful swelling. MRI showed a cortical expansion and bone destruction (Figure 2). Diagnosis was made based on fine needle aspiration (FNA) and biopsy. The patient underwent a chemotherapy course but did not respond to the treatment. After chemotherapy, he did not take any medicine and referred to the physician’s office with swelling in right clavicule in 30<sup>th</sup> January, 2021. 3 months after the end of chemotherapy, the claviculectomy surgery was performed without reconstruction. He underwent the sub-total clavicular resection surgery at Razavi Hospital, Mashhad, Iran. Tumor swelling was 3 x 4 cm and the length of the excised clavicle was about 7 cm (Figure 3). Two months after the surgery, he was followed up and stated no issues. Figure 4 has shown light micrograph with a numerous fusiform osteoblastic cells.
Chondroblastic,Osteosarcomas,Clavicle
https://jctm.mums.ac.ir/article_18256.html
https://jctm.mums.ac.ir/article_18256_6fe8da4b2571ff7bfa7f8dc1cb52a323.pdf