TY - JOUR ID - 18184 TI - The Effect of Curcumin on HDL Cholesterol Uptake Capacity in Obese Individuals: A Pilot Study JO - Journal of Cardio-Thoracic Medicine JA - JCTM LA - en SN - 2345-2447 AU - Saberi-Karimian, Maryam AU - Nosrati, Mina AU - Orooji, Arezoo AU - Kazemi, Tooba AU - Javandoost, Ali AU - Mohammadi, Akram AU - Ferns, Gordon A. AU - Aghasizadeh, Malihe AU - Ghayour-Mobarhan, Majid AD - Lung Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran AD - International UNESCO center for Health Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran AD - Student Research Committee, Department of Epidemiology and Biostatistics, Faculty of Health, Mashhad University of Medical Sciences, Mashhad, Iran. AD - Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran AD - Brighton & Sussex Medical School, Division of Medical Education, Falmer, Brighton, Sussex BN1 9PH, UK. Y1 - 2021 PY - 2021 VL - 9 IS - 3 SP - 833 EP - 838 KW - Curcuma longa KW - Curcumin KW - Cholesterol Uptake Capacity KW - metabolic syndrome DO - 10.22038/jctm.2021.58306.1336 N2 - Introduction: Obesity is a common risk factor associated with cardiovascular disease (CVD) risk. Curcumin has been reported to exert beneficial effects on lipid metabolism, including HDL functionality. We have examined the effects of curcumin on HDL cholesterol uptake capacity in subjects with obesity.Materials and Methods: 30 obese individuals received curcumin and placebo 1 g per day for a period of 30 days. The subjects were crossed over to the alternative regimen after a 2-week washout period. A modified cholesterol uptake capacity (CUC) assay was used to determine serum HDL functionality.Results: The study groups had similar base line characteristics. We did not find significant effects (p>0.05) of curcumin on serum HDL CUC levels.Conclusion: Curcumin administration at a dose of 1 g per day for 30 days did not affect HDL CUC in subjects with obesity. UR - https://jctm.mums.ac.ir/article_18184.html L1 - https://jctm.mums.ac.ir/article_18184_2fd8193936974a19e0e07fa78cfc6daf.pdf ER -