Incidence of Bacterial Endocarditis after Heart Valves Replacement Surgery in Mashhad (from 2012 to 2016)

Document Type : Original Article


1 General Physician, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

2 Department of cardiac surgery, Faculty of medical science, Farshchian Heart Center, Hamedan University of Medical Sciences, Hamedan

3 Department of Cardiac Surgery, Faculty of Medical Science. Mashhad University of Medical Sciences, Iran.

4 ASSISTANT PROFESSOR of cardiac surgery, Department of cardiac surgery, Faculty of medical science, Mashhad University of Medical Sciences .Iran

5 Student Research Committee, Faculty of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.



Introduction: Bacterial endocarditis is one of the high mortality complications after the valve surgery. Despite the medical advancements, the mortality rate of Bacterial Endocarditis has not been decreased. We designed this study to determine the epidemiology of Bacterial Endocarditis following surgery.
Materials and Methods :  This is retrospective study  from 2012 to 2016 in  Mashhad University of Medical Science. Patients with history of Cardiac Surgery with Implantation of Prosthetic valve .The diagnostic method of bacterial endocarditis was based on the Duke’s criteria, Transthoracic echocardiography, and culture lab.
Results: Among 2802 patients with cardiac valve surgery, 9 patients had developed Bacterial endocarditis. The common infectious valve was mitral (58.4%) and prosthetic valves were mostly used in general (77%). There was no relationship between gender (p=0.47), marital status (p=0.68), and type of surgery (p=0.29) and Bacterial endocarditis. But there was a significant relationship between the type of valve surgery and Bacterial endocarditis (p=0.01). Also, 3 patients with Bacterial endocarditis had a history of smoking and drugs. Three patients also died and were excluded.
Conclusion: Bacterial endocarditis differ according to the different studies and our results were compatible with previous studies. Our study confirmed that the utilization rate of the prosthetic valve was higher than the homograft valve. The use of antibiotics should be evaluated prior to performing a culture test which could affect the test results and consequences of the study.


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