Document Type : Case Report
Department of Molecular Genetic, Medical laboratory, Imam Hosein Hospital, Mashhad, Iran.
Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Iranian UNESCO Center of Excellence for Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Neurology, Gaem Hospital, Mashhad Univeristy of Medical Sciences, Mashhad, Iran.
A new infection emerged into the world which has been declared a global pandemic in December 2019, termed SARS-CoV-2 based on its first pulmonary manifestations. Also, Neurologic consequences can be disturbing complications of these respiratory viral diseases.
Here we present a 51-year-old nurse with motor-sensory symptoms following developed mild coryza symptoms including sore throat, general malaise, and conjunctivitis. However, a week of ocular muscle discomfort and weakness preceded coryza symptoms. She was returned negative by nasopharyngeal swab test twice for detection of the SARS-Cov-2 genome by a real-time polymerase chain reaction (PCR) and Chest X-Ray (CXR) examination. Since the patient had neurological symptoms, MRI was performed, which showed inflammation in the spinal cord and meninges.
Cerebrospinal fluid (CSF) fluid investigation for immunological and Covid-19 examination showed SARS-Cov-2 involvement in this patient. The patient's characteristics show that the involvement of Covid-19 is not limited to the lungs or gastrointestinal tract, and the nervous system, despite the presence of a brain barrier, can be invaded by the virus. From this point of view, we should expect a shadow of the involvement of different parts of the nervous system in Covid-19.