Journal of Cardio-Thoracic Medicine

Journal of Cardio-Thoracic Medicine

Determination of The Relationship Between Severity of Obstructive Sleep Apnea And Chronic Obstructive Pulmonary Disease

Document Type : Original Article

Authors
Vahid Dehestani 1
Fariba Rezaeetalab 2
Mahnaz Amini 2
Davood Attaran 2
Leila Ghofraniha 2
Mohammadreza kasraei 2
1 Fellow of Pulmonology, Lung Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
2 Pulmonologist, Lung Disease Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
10.22038/jctm.2016.7416
Abstract
Introduction: Chronic obstructive pulmonary disease (COPD) patients are at increased risk of sleep-disorders. The concomitant occurrence of COPD and obstructive sleep apnea hypopnea syndrome (OSAHS) is named overlap syndrome. This study aimed to evaluate the severity of OSAHS in overlap syndrome patients.
Materials & Methods: This cross-sectional study was conducted on adult patients with forced expiratory volume in 1 second (FEV1%)/forced vital capacity
Results: Forty patients (62.5% male) with mean age of 59.7±8.3 years participated in the study. Severity of obstructive sleep apnea was low, moderate, and severe in 23 (57.5%), 14 (35%), and 3 (7.5%) cases, respectively and there was no statistical relation between OSAHS and FEV1% (P=0.55).
Conclusion: This study showed that there was no significant correlation between apnea–hypopnea index and FEV1% predicted in overlap syndrome patients.
Keywords
Apnea Hypopnea Index
Body mass index
Chronic Obstructive Pulmonary Disease
Obstructive Sleep Apnea Hypopnea Syndrome
Overlap Syndrome
  1. Buist AS, Anzueto A, Calverley P, deGuia TS, Fukuchi Y, Jenkins C, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. London: Global Initiative for Chronic Obstructive Lung Disease (GOLD); 2006.
  2. Rezaeetalab F, Attaran D, Lari S, Basiri R, Ghofraniha L, Dehestani V. The evaluation of diastolic hypertension in sleep overlap syndrome. J Cardiothorac Med. 2015; 3:259-62.
  3. Partida-Gaytán A, Berber A, del Río-Navarro BE, Haro-Valencia R. Frequency and severity of OSAHS in Mexican adolescents: the role of BMI and neck circumference. Health. 2013; 5:1-8.
  4. Mirzazadeh A, Osooli M, Salimzadeh H, Arabi M, Navade K, Haghdoost A, et al. A meta-analysis of body mass index Trends in Iran: last 15 years. Sci Health. 2000; 5:59 (Persian).
  5. Herer B, Roche N, Carton M, Roig C, Poujol V, Hughon G. Value of clinical, functional and oximetric data for the prediction of obstructive sleep apnea in obese patients. Chest. 1999; 116:1537-44.
  6. Chaouat A, Weitzenblum E, Krieger J, Ifoundza T, Oswald M, Kessler R. Association of chronic obstructive pulmonary disease and sleep apnea syndrome. Am J Respir Crit Care Med. 1995; 151:82-6.
  7. Teodorescu M, Consens FB, Bria WF, Coffey MJ, McMorris MS, Weatherwax KJ, et al. Predictors of habitual snoring and obstructive sleep apnea risk in patients with asthma. Chest. 2009; 135:1125-32.
  8.  Rezaeetalab F, Rezaeitalab F, Dehestani V. Inhaled steroids reduce apnea-hypopnea index in overlap syndrome. Pneumologia. 2013; 62:212-4.
  9. Owens RL, Malhotra A. Sleep-disordered breathing and COPD: the overlap syndrome. Respir Care. 2010; 55:1333–44.
Journal of Cardio-Thoracic Medicine
Volume 5, Issue 1
Winter 2017
Pages 530-532