Outcomes of On-pump Coronary Artery Bypass Grafting in Patients with Metabolic Syndrome in Mashhad, Iran

Document Type : Original Article


1 Atherosclerosis Prevention Research Center, cardiac surgery Imam Reza Hospital, Mashhad University of Medical Sciences,

2 Assistant professor, Department of cardiac surgery, Atherosclerosis Prevention Research Center ,Faculty of medical science, Mashhad University of Medical Sciences, Iran

3 Assistant Professor of Community Medicine, Faculty of medical science, Imam Reza Clinical Research Units, Mashhad University of Medical Sciences

4 Student Research Committee, Faculty of medicine, Mashhad University of Medical Sciences, Mashhad, Iran

5 - Student Research Committee, Faculty of medicine, Mashhad University of Medical Sciences, Mashhad,

6 Veterinary student.mashhad Ferdowsi scenice university

7 Assistant professor, Department of cardiac surgery, Faculty of medical science. Hamadan University of Medical Sciences, Mashhad, Iran.


Introduction: Metabolic syndrome (MS) is considered as an important risk factor for advanced coronary artery disease. This condition can increase the mortality and morbidity in the patients undergoing coronary artery bypass graft (CABG) surgery. The aim of the study was compared mortality and morbidity after off Pump- CABG surgery between patients with and without the Metabolic syndrome.
Materials & Methods: This prospective cross-sectional study was conducted on 120 patients, who underwent off-pump CABG surgery between October 2014-October 2016. The participants were equally divided into two groups including the patients with and without MS (MS and non-MS, respectively).
Results: According to the results, 68 (56.6%) patients were male. Furthermore, out of the 60 participants with MS, 36 (60%) cases were male. The mean ages of the MS and non-MS groups were 64.96±9.6 and 65.62±10.6 P=0.6 years, respectively. No statistically significant difference was observed between the two groups in terms of the mortality and morbidity (e.g., surgical wound infection, length of Intensive Care Unit and hospital stay, atrial fibrillation rhythm, and bleeding in the first 24 h). The intubation time in patients with Metabolic Syndrome was significantly higher than patients without Metabolic Syndrome (6.66 ± 1.97 vs 5.83 ± 1.93 respectively; P=0.007)
Conclusion: Metabolic syndrome was not associated with higher mortality and morbidity after CABG surgery compare to patients without Metabolic syndrome, although patients with Metabolic syndrome had higher risk for long intubation time.


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